Senior Director Biostatistics, Head of Statistical Innovation & Methodology

Responsibilities:

• Lead the identification, development, evaluation, and application of innovative statistical methodologies to support clinical development programs.
• Conduct and oversee methodological research on emerging statistical approaches, and guide the development of tools, algorithms, and analytical frameworks.
• Provide expert statistical consultation to clinical development teams, influencing program-level decisions through rigorous quantitative evaluation.

Qualifications:

• PhD in Statistics, Biostatistics, or related quantitative discipline with 12+ years of pharmaceutical or biotechnology industry experience.
• Strong expertise in clinical trial design, modern statistical methodologies, and simulation-based evaluation.
• Proven track record in adaptive designs, Bayesian methods, or model-based decision frameworks.

About Alnylam:

• We are the leader in RNAi therapeutics, with a deep pipeline and late-stage programs.
• We foster an authentic, inclusive culture and are committed to breakthrough thinking.
• We offer competitive benefits and are an equal opportunity employer.