Integrating the ADME characteristics of drug candidate molecules.
Provides in vitro to in vivo translation, human dose predictions, and clinical using compartmental PK and PBPK and PD.
Focus on Antibody-Drug Conjugates (ADCs), specifically on the mechanistic PBPK modeling for their payloads.

Job Description:

Comprehensive characterization of ADC payload ADME using both internal and published data.
Independent development and validation of PBPK model for ADC payloads in Simcyp.
Integration of mechanistic data or QSAR-predicted parameters to ensure broad applicability of models.

GSK

GSK is a global biopharma company uniting science, technology, and talent to get ahead of disease together. They focus on the science of the immune system and the use of new platform and data technologies. GSK wants to be a place where people feel inspired, encouraged and challenged to be the best they can be.

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