Job Description
Lead the design, development, and validation of R/Python code to automate generation of analytical datasets and TLFs within a metadata-driven pipeline. Translate SAPs and metadata specifications (YAML/CSV) into executable and reproducible code. Build and validate R packages and data science tools supporting both exploratory and confirmatory analyses, ensuring full traceability and audit readiness. Implement and validate statistical models (e.g., MMRM, ANCOVA, logistic regression) using R packages such as mmrm, emmeans.
Collaborate with IT to integrate data science and statistical programming workflows within Databricks and CI/CD pipelines for continuous validation and reproducibility. Collaborate across programming, biostatistics, and data standards functions to ensure dataset definitions, derivations, and metadata align with controlled standards. Conduct peer code reviews, unit testing, and automated validation; ensuring deliverables meet submission-quality and reproducibility standards. Mentor and guide team members in best practices for programming, validation, and automation.
About Praxis Precision Medicines
Praxis Precision Medicines is a clinical-stage biopharmaceutical company translating genetic insights into the development of therapies for central nervous system disorders.