Senior Medical Director, Clinical Development

Spyre Therapeutics

Remote regions

US

Salary range

$343,000–$365,000/yr

Benefits

Unlimited PTO

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Role Summary:

  • Contribute to clinical development strategy and execution for rheumatic indications.
  • Play key role in global clinical development programs, partnering with cross-functional teams.
  • Direct research and strategy to drive program success at an early stage.

Key Responsibilities:

  • Provide strategic leadership and medical expertise for antibody portfolio.
  • Manage trial design, execution, and interpretation of results.
  • Collaborate with Biostatistics, Regulatory Affairs, and Clinical Operations.
  • Ensure safety monitoring and compliance with regulatory standards.

Ideal Candidate:

  • MD or equivalent medical degree required.
  • Minimum 4+ years clinical development experience in I&I, rheumatology preferred.
  • Proven track record in designing and executing clinical trials in immunology.
  • Strong understanding of GCP, statistics, and global regulatory processes.

What We Offer:

  • Opportunity to work in a fast-paced, dynamic environment.
  • Market competitive compensation, including base salary, bonus, equity, and benefits.
  • Unlimited PTO and two company-wide shutdowns each year.
  • Remote working environment with in-person meetings.

Spyre Therapeutics

Spyre Therapeutics is a clinical-stage biotechnology company committed to developing next-generation therapies in immunology. The company is a young, fast-paced organization with a pipeline of investigational extended half-life antibodies, offering a remote working environment.

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