Source Job

US

  • Lead chemistry efforts on cross-functional project teams to drive PROTAC programs from inception to clinical candidate nomination.
  • Design molecules with optimized potency, selectivity, and pharmacokinetic properties, focusing on degrader-antibody conjugates.
  • Collaborate with computational chemistry, CROs, and cross-functional partners to analyze SAR and inform strategic decisions.

2 jobs similar to New Medicinal Chemistry Project Leader

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US

  • Lead and manage internal chemistry resources and CRO teams to identify IND-ready candidate molecules.
  • Serve as chemistry leader within multidisciplinary project teams, building effective relationships across geographically dispersed collaborators.
  • Use SAR analysis and computational tools to design novel molecules and establish intellectual property.

Centessa Pharmaceuticals is a clinical-stage company developing orexin receptor 2 (OX2R) agonists as a new class of medicines for the treatment of narcolepsy and potentially other sleep-wake disorders. Headquartered in Boston, Massachusetts, it was recognized as a Great Place to Work in 2026.

US

  • Define and drive asset strategy for small molecule clinical programs in oncology and immunology/inflammation, integrating competitive positioning and biomarker strategy.
  • Translate Recursion OS and ClinTech insights into strategic advantages, ensuring proprietary data and computational insights maximally enable drug discovery and development.
  • Partner with functional leaders across clinical development, BD, finance, and platform teams to align resource allocation with strategic conviction and impact.

Recursion is a clinical-stage TechBio company decoding biology to improve lives, advancing a pipeline of investigational medicines across oncology, rare disease, neuroscience, and immunology. The company uses its AI-native Recursion OS platform and employs a team fluent in both science and AI, with offices in Salt Lake City, Oxfordshire, New York, Montréal, and London.