Scientific Narrative Lead

Role Overview:

• Own the strategic scientific narrative for a lead Praxis program, building deep fluency in its science, data, development strategy, competitive context, and potential value to patients.
• Build and maintain a forward-looking narrative and communications roadmap that connects program strategy, emerging evidence, key milestones, regulatory interactions, publications, and launch preparation.
• Serve as a connective thread across Clinical Development, Clinical Pharmacology, Nonclinical, Regulatory Affairs, Biostatistics, Data Management, Quality, CMC, Medical Affairs, and Commercial, identifying inconsistencies early and driving alignment around the evidence.

Key Responsibilities:

• Shape scientific positioning and key messages in critical clinical and regulatory documents (protocols, IBs, CSRs, briefing docs, clinical overviews, integrated summaries).
• Set narrative direction for US and global regulatory submissions, partnering with Regulatory Affairs and Clinical Development to ensure consistent, rigorous storytelling.
• Anticipate how new data, regulatory feedback, competitive developments, and program decisions impact the scientific story and advise leadership accordingly.

Qualifications & Culture:

• Bachelor’s degree in a scientific discipline required; advanced degree preferred; CNS, neuroscience, or rare disease experience a plus.
• 6+ years in biopharma, CRO, or consulting with experience in scientific communications, regulatory strategy, or medical affairs.
• Praxis values trust, ownership, curiosity, and results, with a collaborative culture focused on developing high-impact therapies for neurological disorders.