Principal AI/ML Platform Engineer

The Principal AI/ML Platform Engineer is responsible for build and delivery of the next generation of Natera’s Generative AI and ML platforms. This is a hands-on technical leadership role at the intersection of engineering excellence, platform design, and applied GenAI/ML innovation. This role requires deep expertise in AI engineering at scale, with a passion for building robust, compliant, and high-performance systems that directly impact patient outcomes and clinical innovation.

You will design, build, and scale enterprise-grade Gen AI and ML platforms and services that power internal workflows (R&D, Lab Ops, Clinical Trials, Billing, Patient/Provider engagement) and external-facing AI/ML products. As the most senior leader in the AI/ML engineering team, you will also set technical standards, mentor engineers, and drive adoption of cutting-edge techniques such as retrieval-augmented generation (RAG), advanced prompt engineering, vector search, GenAI governance, evaluation frameworks, ML/LLMOps, model experimentation, observability, and compliance-first AI pipelines. You will be responsible for development of a production-ready AI platform with reusable components used to deploy multiple AI solutions across Natera’s business units in a federated approach. You will also develop clear standards and best practices established for AI/ML development across the organization.