Oversee medical safety activities and processes for assigned products, ensuring continuous assessment of safety profiles and benefit-risk of investigational and marketed compounds. Provide patient-focused leadership for medical safety, support asset strategies, and strengthen medical and scientific innovation. Timely escalation of safety issues to the Takeda Safety Board Chair is required.

Support drug safety and risk management activities across Orca Bio's clinical programs including signal detection, evaluation and management. Assist in the development of risk management strategy and activities for programs, including providing content for RMPs and preparing responses for regulatory authority safety requests. Support safety in clinical trials with review of protocols. Lead the planning, writing and review of periodic safety reports.