In this role, you will closely collaborate with other statisticians and provide statistical-methodological expertise on multiple topics: integration of external data into clinical development and HTA reports, complex evidence synthesis, patient-focused drug development, clinical trial design, and real world evidence methodology. You will evaluate advanced statistical methods to foster holistic evidence generation by prototyping and developing ready-to-use toolkits.

Responsible for protocol development including study design, sample size calculation, randomization, and statistical analysis plan for assigned studies. Provide statistical oversight to studies and assure adequate quality and consistency with project requirements. Responsible for assuring that data for statistical analyses are complete, accurate and consistent.

Apply your scientific expertise to the development of early, noninvasive tests for cancer detection. With a strong background in NGS assay development, bioinformatics, statistics, and molecular biology, you will design and execute research studies to drive early research of prototype cancer early detection products using cfDNA as biomarker. In collaboration with wet lab scientists, rapidly characterize and iterate on experimental methods by providing real-time assessments of assay performance, quality control, and clinical/diagnostic utility.

The Senior Principal Statistician will be responsible for protocol development and statistical analysis plans for assigned studies providing statistical oversight to studies and ensuring adequate quality and consistency with project requirements. Additional responsibilities include assuring data accuracy and timeliness of statistical input into reports or decisions and effectively mentoring peers, managing activities of statisticians across projects.