Contribute strategic leadership and medical expertise to clinical development of antibody portfolio in rheumatic indications.
Design and execute clinical trials, focusing on proof-of-concept and later phases, with cross-functional collaboration.
Provide medical input for regulatory documents, ensure safety oversight, and engage with stakeholders.
Spyre Therapeutics is a clinical-stage biotechnology company committed to developing next-generation therapies in immunology. The company is a young, fast-paced organization with a pipeline of investigational extended half-life antibodies, offering a remote working environment.
Lead design and execution of clinical trials for novel antibody-based therapies in rheumatology and I&I diseases.
Collaborate cross-functionally with clinical operations, regulatory, translational science to ensure robust study designs and data quality.
Interpret clinical data and present findings internally and externally, supporting regulatory submissions and scientific publications.
Spyre Therapeutics is a clinical-stage biotechnology company developing next-generation therapies for immunology diseases. As a small, young company, it fosters a fast-paced, collaborative culture focused on advancing meaningful medicines for patients.
Lead and personally execute biologics CMC consulting engagements as the primary technical point of contact across program lifecycle.
Establish and grow Syner-G's presence in the West Coast biologics market, focusing on Bay Area, San Diego, and Seattle biotech corridors.
Provide expert guidance across biologics development including upstream and downstream process development, analytical characterization, and CMC regulatory strategy.
Syner-G is a strategic biopharma product development and delivery partner that accelerates breakthrough science and delivery of life-enhancing therapies. The company has been honored with BioSpace's prestigious 'Best Places to Work' award for three consecutive years, fostering a culture focused on career growth, development opportunities, and financial rewards.
Accountable for translational development strategy from drug candidate through IND submission and Phase 1 entry.
Support biomarker strategies, indication selection, and patient stratification to guide program decisions.
Lead IND-enabling activities, author regulatory documents, and serve as translational science lead in FDA interactions.
We are a small, driven biotech company using Nobel Prize-winning click chemistry to develop targeted cancer therapies that activate potent drugs only at the tumor site. We are a remote-first team encompassing broad backgrounds, united by a mission to make cancer treatments more effective with minimal side effects.
Lead the biometrics team including statisticians, data managers, and statistical programmers at a program level, providing strategic input for clinical development.
Author and develop Statistical Analysis Plans (SAPs), contribute to trial designs, protocol development, and sample size calculations, and oversee vendor deliverables.
Interact with global health authorities, contribute to regulatory submissions, and coordinate statistical analyses for safety updates and ad hoc requests.
Spyre Therapeutics is a clinical-stage biotechnology company developing next-generation long-acting antibodies to redefine the standard of care for inflammatory bowel disease and rheumatic diseases. As a growing company, they offer a fast-paced, dynamic environment where you help shape the culture and contribute broadly to meaningful medicines.