Source Job

$160,000–$180,000/yr
US

  • Lead end-to-end TMF strategy, including transition from outsourced to in-house operations.
  • Ensure TMF health and inspection readiness through governance, quality control, and metrics.
  • Serve as TMF subject matter expert and partner cross-functionally for document flow and compliance.

Regulatory Compliance Clinical Research Cross-functional Leadership

6 jobs similar to Associate Director, TMF Lead

Jobs ranked by similarity.

US

  • Lead TMF activities for clinical trials across start-up, maintenance, close-out, and archive phases.
  • Oversee eTMF health, quality issue workflows, and compliance with regulatory standards.
  • Support TMF document processing, audits, and continuous improvement initiatives.

Akero Therapeutics is a clinical stage biopharmaceutical company focused on developing transformational treatments for serious metabolic diseases such as MASH. They are part of Novo Nordisk and foster a collaborative culture with diverse skill sets.

Netherlands

  • Manage TMF operations activities for multiple complex studies or sponsor portfolios.
  • Oversee Trial Master File quality control including planning, tracking, and reporting.
  • Support regulatory inspections and sponsor audits while collaborating with cross-functional teams.

This is a global clinical research environment focused on ensuring accuracy, compliance, and quality of essential trial documentation. The company operates with a collaborative international team and values inclusion, professional growth, and purpose-driven healthcare work.

Latin America

  • Oversee Trial Master File (TMF) activities including document review, quality checks, and study-level engagement to ensure regulatory compliance.
  • Manage a team of Documents Specialists, Quality Review Specialists, and TMF Leads, providing training, performance management, and support.
  • Collaborate with leadership to drive process improvements and ensure efficient records management across clinical programs.

Precision Medicine Group is a contract research organization providing clinical research services. The company is expanding across Latin America and fosters a collaborative, quality-focused culture.

LATAM

  • Ensure timely review, processing, and quality of Trial Master Files (TMF) according to GCP and SOPs.
  • Create and execute study TMF plans, manage document indexing, and communicate changes to project teams.
  • Monitor TMF health, identify risks, and support audits and inspections for compliance.

Precision Medicine Group is a global contract research organization providing clinical trial support and precision medicine services. The company values professionalism, collaboration, and quality, with a focus on maintaining inspection-ready trial master files.

Global

  • Provides study-level oversight and leadership for global clinical trials from inception through closure, managing vendors, recruitment, and cross-functional teams.
  • Develops and manages study materials including protocols, regulatory submissions, and budgets while ensuring compliance with quality standards and inspection readiness.
  • Contributes to system management like EDC, IRT, and eTMF, and supports process improvement initiatives or serves as a mentor.

AbbVie discovers and delivers innovative medicines and solutions to address serious health issues in immunology, oncology, neuroscience, and aesthetics. As a global biopharmaceutical company with a robust pipeline, they emphasize integrity and innovation, serving patients worldwide with a dedicated team.

$145,000–$165,000/yr
US

  • Independently manage all operational aspects of Phase I clinical trials from startup through closeout, ensuring adherence to protocols and regulations.
  • Oversee CROs and vendors to ensure alignment with study goals, budget, and timelines.
  • Lead the company-wide rollout of Veeva Vault, serving as a primary operational user and subject matter resource.

Absci is a clinical-stage biotechnology company leveraging generative AI for drug discovery through its Integrated Drug Creation platform. The company has a global presence with offices in the US, Switzerland, and Serbia, and fosters a collaborative, innovative culture.