Source Job

$129,100–$163,000/yr
US

  • Own end-to-end Nextflow workflow execution: run launch, configuration, tracking, retries/failures, metadata capture, and auditability on AWS Batch.
  • Build internal web apps and services that enable operational workflows (e.g., custom panel design, QC/reporting, run monitoring).
  • Integrate pipeline events and outcomes with Slack, Jira, and HubSpot to support scalable operations.

Python React AWS HPC APIs

20 jobs similar to Staff Bioinformatics Engineer

Jobs ranked by similarity.

US

  • Working with the Data Science Production Engineering team, to design and develop a Genomics Data System.
  • Develop genomics data file retrieve and archive solutions from various data sources and platforms, e.g., DNAnexus, AWS HealthOmics.
  • Develop databases that record and manage metadata of the genomics data files.

Natera is a global leader in cell-free DNA (cfDNA) testing, dedicated to oncology, women’s health, and organ health. They aim to make personalized genetic testing and diagnostics part of the standard of care. The Natera team consists of highly dedicated statisticians, geneticists, doctors, laboratory scientists, business professionals, software engineers and many other professionals from world-class institutions, who care deeply for their work and each other.

US

  • Develop and improve analysis pipelines for diagnostic tests, including detection of cancer-associated variants or methylation patterns and implementation of evidence-based quality control thresholds.
  • Leverage accurate statistical or probabilistic models to build the next round of algorithms and products.
  • Move products through the full development process, from research through commercial launch.

They are a global leader in cell-free DNA (cfDNA) testing, dedicated to oncology, women’s health, and organ health. The Natera team consists of highly dedicated statisticians, geneticists, doctors, laboratory scientists, business professionals, software engineers and many other professionals from world-class institutions, who care deeply for their work and each other.

Latin America

  • Design and implement backend architecture to shape the platform.
  • Build GraphQL APIs for querying and analyzing genetic construct data.
  • Develop services using Python, SQLAlchemy, and modern backend frameworks.

This innovative company is developing a synthetic biology platform, combining biology, software engineering, and advanced computation to accelerate the development of next-generation therapeutics. They are building tools that transform biological engineering into a true engineering discipline.

$133,500–$166,900/yr
US

  • Develop and improve analysis pipelines for diagnostic tests.
  • Leverage accurate statistical or probabilistic models to build algorithms and products.
  • Move products through the full development process, from research through commercial launch.

Natera is a global leader in cell-free DNA (cfDNA) testing, dedicated to oncology, women’s health, and organ health. The Natera team consists of highly dedicated statisticians, geneticists, doctors, laboratory scientists, business professionals, software engineers and many other professionals from world-class institutions, who care deeply for our work and each other.

$150,000–$180,000/yr
US

  • Design and implementation of reliable, maintainable, and scalable GenAI systems.
  • Serve as a subject matter expert for machine learning systems owned by the team.
  • Mentor junior and mid level engineers through code reviews and design collaboration.

Trajector specializes in medical evidence services, guiding clients through disability benefits complexities. They are a global team of over 1,800 dedicated individuals, streamlining the path to benefits and ensuring access to rightful compensation for those with disabilities.

$170,000–$190,000/yr
US

  • Lead and Steer technical deliverables, mentor engineers, and collaborate with stakeholders to translate business needs into technical reality.
  • Architect scalable solutions for document generation that integrate seamlessly with data science and clinical platforms.
  • Build and maintain developer tooling that supports the wider team, ensuring that local development environments mirror production as closely as possible.

Arine is a healthcare technology and clinical services company with a mission to ensure individuals receive the safest and most effective treatments. Backed by leading healthcare investors, they manage more than 18 million lives across prominent health plans and were ranked 236 on the 2024 Inc. 5000 list.

US

  • Lead and scale a 100+ engineer organization through Directors and Sr. Directors
  • Improve delivery predictability, engineering velocity, and production quality
  • Strengthen planning, estimation, and development processes

Natera is a global leader in cell-free DNA (cfDNA) testing, dedicated to oncology, women’s health, and organ health. The Natera team consists of highly dedicated statisticians, geneticists, doctors, laboratory scientists, business professionals, software engineers and many other professionals from world-class institutions, who care deeply for our work and each other.

North America

  • Partner with Sales to qualify opportunities and lead technical discovery.
  • Design and deliver compelling demos adapting to both technical and executive audiences.
  • Own the technical POC process ensuring clean handoffs into production.

Andromeda Cluster gives early-stage startups access to scaled AI infrastructure. They work with AI labs, data centers, and cloud providers to deliver compute when and where it’s needed most to build the liquidity layer for global AI compute.

$171,600–$224,300/yr
US Unlimited PTO

  • Build and integrate tools to optimize contracting, eligibility, and billing processes.
  • Identify ways to improve, mentor others, and remove ambiguity as an informal team leader.
  • Leverage AI and ML tooling to deliver innovative solutions to complex problems.

Omada Health is a digital care provider that empowers people to achieve their health goals through sustainable behavioral change. They strive to build an inclusive culture where differences are celebrated and leveraged to inform better design and business decisions.

US

  • Define the enterprise strategy for Production-Grade Bioinformatics, ensuring pipelines are robust, reproducible, and version-controlled for clinical use.
  • Enable seamless integration between the “Dry Lab” results and “Wet Lab” QC metrics to deliver both operational and scientific insights to reviewers and lab directors.
  • Ensure data architectures comply with global privacy standards (HIPAA, GDPR) while maintaining the high availability required for clinical operations.

Natera is a global leader in cell-free DNA (cfDNA) testing, dedicated to oncology, women’s health, and organ health, aiming to make personalized genetic testing the standard of care. They consist of statisticians, geneticists, doctors, scientists, business professionals, and engineers from world-class institutions.

Global

  • Design, build, and maintain scalable backend services primarily using Python
  • Develop and operate cloud-native systems on AWS, ensuring reliability, security, and performance
  • Contribute to infrastructure design and automation using Terraform

Smart Working connects skilled professionals with global teams for full-time, long-term roles, breaking down geographic barriers. They value growth and well-being, fostering a genuine community and empowering individuals to thrive in a remote-first world.

US

  • Analyze single-cell and multiomics datasets to extract biological insights supporting precision medicine and drug development programs
  • Apply and evaluate machine learning and deep learning approaches to single-cell data for tasks such as cell type classification, biomarker discovery, and patient stratification
  • Explore and prototype generative AI and LLM-based approaches to accelerate biological data interpretation and scientific workflows

RefinedScience's mission is to advance care by bringing together the best science, data and minds – disease by disease, patient by patient, cell by cell to discover pathways to life beyond disease. They seamlessly integrate top-tier clinical and biological data with expert knowledge to provide unparalleled insights.

$146,000–$252,000/yr
US Global

  • Architect, build, and maintain highly scalable batch and streaming pipelines on the Snowflake Data Platform.
  • Architect and deliver ML/GenAI solutions using managed cloud services.
  • Implement modern data modeling and architecture patterns; establish and enforce standards for data quality.

FUJIFILM Biotechnologies focuses on making the next vaccine, cure, or gene therapy in partnership with some of the most innovative biopharma companies across the globe. They cultivate a culture that will fuel your passion, energy, and drive.

Global

  • Collaborate with product management and stakeholders to deliver SaaS solutions.
  • Design, develop, and maintain backend services using Python and FastAPI for agentic workflows.
  • Contribute to developing multi-agent systems and integrate agents with third-party tools.

Granicus is dedicated to transforming the Govtech industry by uniting governments and constituents through technology. They offer cloud-based solutions for communications, website design, meeting management, and digital services, empowering stronger relationships between government and residents. The company has 5,500 federal, state, and local government agency customers.

$140,000–$160,000/yr
US 4w PTO

  • Own and evolve the data infrastructure that powers Clever's core data products.
  • Maintain and improve data pipeline reliability, monitoring and resolving pipeline failures.
  • Design and implement ingestion for new operational data sources that support Clever's speed-to-match initiative.

Clever Real Estate is a venture-backed technology company aiming to revolutionize real estate transactions. They have built a leading online education platform helping consumers save money and have earned a 4.9 TrustPilot rating with over 3,800 reviews.

$130,000–$170,000/yr
US

  • Drive the development of robust, scalable applications using a serverless-first mindset on AWS.
  • Design, build, and integrate solutions that utilize agentic AI, applying modern AI design patterns to automate and enhance complex workflows.
  • Champion modern, AI-assisted software engineering processes, leveraging tools like Claude Code to multiply team’s effectiveness.

Trajector specializes in medical evidence services, guiding clients through disability benefits. As part of a global team of over 1,800, they streamline the path to benefits, driven by urgency and data to improve lives.

$160,800–$193,000/yr
US Unlimited PTO

  • Create robust pipelines to process massive daily volumes of data.
  • Build and support scalable pipelines as part of Torc’s Data Factory.
  • Scale Torc’s data lake through a distributed storage system.

Torc has been a leader in autonomous driving since 2007 and is now part of the Daimler family, focused on developing software for automated trucks. Their culture is collaborative, energetic, and team-focused, offering flexibility and valuing work/life balance.

$140,000–$180,000/yr
US

  • Participate in the decisions on “how” we deliver software.
  • Partner on the “what, when, who and why” of our software with Design and Product.
  • Lead a major feature or application and support junior engineering talent with mentorship and/or technical guidance.

Nooks is pioneering Classified Infrastructure-as-a-Service (CIaaS) to provide government and industry partners with the fastest, most efficient access to classified infrastructure. As a startup, they are offering a limited-time opportunity to be an equity owner in a pioneering new industry and they value innovation, collaboration, and a service-first mindset.

Global

  • Architect our AWS-based data warehouse and ingestion pipelines.
  • Transform high-volume simulation outputs into clean, trusted datasets.
  • Establish schema standards and data contracts with engineering.

Onebrief provides collaboration and AI-powered workflow software designed for military staffs, making them faster, smarter, and more efficient. The company, founded in 2019, values ownership and excellence, with a team spanning veterans and technologists; it has raised $320m+ from investors and is valued at $2.15B.

$160,000–$200,000/yr
US

  • Lead the design, development, and delivery of enterprise-grade, customer-facing web applications using modern microservices architectures.
  • Provide senior technical leadership through architecture decisions, design reviews, and code reviews, ensuring scalability, reliability, security, and maintainability.
  • Manage, mentor, and grow a distributed team of software and quality engineers, fostering a culture of ownership, accountability, and continuous improvement.

Firstup's mission is to improve the employee experience. They serve 40 of the Fortune 100 companies, reaching and connecting more than 17 million employees daily and are experts in the employee experience, workforce communications and technology.