Source Job

US

  • Architecting core platform primitives while setting the standard for technical excellence and safety.
  • Designing durable, production-grade systems that power patient engagement and provider workflows at scale.
  • Owning the AI foundation that determines how generative AI shows up across mental healthcare.

Python AWS GCP MLOps GenAI

20 jobs similar to Principal AI Engineer

Jobs ranked by similarity.

US

  • Own technical direction for high-impact AI products.
  • Work across teams to turn big ideas into shipped systems.
  • Help raise the bar for how we build, evaluate, and operate AI in production.

Rula is dedicated to treating the whole person, not just the symptoms, and aims to create a world where mental health is no longer stigmatized. They are a remote-first company that hires in most U.S. states and are passionate about making a positive impact on mental healthcare.

$428–$500/mo
Global

  • Own the complete lifecycle of your assigned workstream.
  • Build AI systems designed to perform consistently and efficiently at scale.
  • Collaborate with our team to translate requirements into maintainable AI solutions.

They are looking for a contract AI Engineer to join them for an active, ongoing project and contribute immediately. Contract performance can lead to repeat engagements.

US

  • Launch and scale AI-powered features that transform the patient experience.
  • Explore how AI can support patients before, during, and after care with their therapist.
  • Build safe, supportive, and personalized AI experiences that enhance care.

Rula provides mental healthcare with AI-enabled experiences. They aim to enhance the human connection at the core of therapy and are a remote-first company with a culture of diversity, equity, and inclusion that supports employees in feeling safe, seen, heard, and valued.

$229,000–$240,000/yr
US

  • Lead AI strategy and execution, integrating AI into core products and accelerating development workflows.
  • Architect and build complex, scalable systems and AI-driven features using technologies like Python, Java, AWS, and GCP.
  • Provide technical leadership, mentorship, and cross-functional collaboration to solve complex problems and drive successful outcomes.

Tebra provides an all-in-one EHR+ platform designed exclusively for independent healthcare practices to connect EHR software, billing, automation, telehealth, and marketing. The company serves over 42,000 private practices and fosters a culture of entrepreneurship, customer focus, simplicity, teamwork, and celebration.

$124,800–$156,000/yr
US

  • Architect, implement, and maintain AI agent orchestration platforms for multi-agent delegation, session management, and streaming interfaces.
  • Design and build Model Context Protocol (MCP) servers to expose domain-specific capabilities as composable tools with rigorous security and isolation.
  • Deploy and operate containerized services on AWS using Terraform, optimizing for cost, reliability, and observability while partnering with ML and data engineers.

Natera is a global leader in cell-free DNA testing dedicated to oncology, women’s health, and organ health, aiming to make personalized genetic testing part of standard care. The company consists of a dedicated team of professionals from world-class institutions who are stretched and challenged while working to change genetic disease management.

US Unlimited PTO

  • Maintain, improve, and extend an AI platform already running in production.
  • Handle a mix of backend development, data pipelines, DevOps, and infrastructure work.
  • Translate business and product requirements into technical decisions independently.

Provectus is an AI consultancy and solutions provider. We help businesses adopt AI technologies, offering development and integration services. While the job posting doesn't mention company size information, they seem to foster a flexible, autonomous, and tech-forward culture.

LATAM

  • Design and build AI systems in production that solve real business problems, end-to-end: from discovery to operation.
  • Work with product and operations to translate ambiguous problems into measurable and maintainable solutions.
  • Build data pipelines that feed models and product surfaces.

Skydropx is innovating logistics with a team of visionary people who want to grow and change the world. They are integrating AI into their logistics platform for LATAM, working at a multi-tenant scale with hundreds of thousands of shipments per month.

  • Consult clients during presales to assess AI readiness and translate visions into actionable requirements.
  • Architect multi-agent frameworks, design AI systems with defined roles, and implement learning & feedback loops.
  • Develop RAG pipelines, design custom models, and ensure governance, security, and cost-efficiency.

Sigma Software is seeking a Senior/Principal AI Engineer to join their Stellar AdTech Business Unit. They deliver innovative systems to global AdTech leaders and startups since 2008, with a strong AdTech competence center of 300+ employees.

$120,000–$160,000/yr
US

  • Design, develop, and deploy AI/ML models to automate and improve internal workflow.
  • Build and maintain ML pipelines within an AWS cloud environment.
  • Integrate ML capabilities into existing Java and React application workflows.

Oddball aims to improve daily lives by delivering quality software to the federal space. With a team of experienced engineering, product, and UX professionals, we value learning, growth, and making a big impact in a rapidly growing company.

AI Engineer

Natera
$105,700–$132,100/yr
US

  • Ship zero-to-one AI products end-to-end — from customer discovery and prototyping through production deployment and iteration
  • Build agentic AI systems — design and implement autonomous and semi-autonomous workflows using LLMs, tool-use, memory, and orchestration
  • Develop AI tools that improve efficiency across clinical operations, data extraction, manual workflows, and more

Natera is a global leader in cell-free DNA (cfDNA) testing, dedicated to oncology, women’s health, and organ health. The Natera team consists of statisticians, geneticists, doctors, scientists, business professionals, software engineers and other professionals from world-class institutions.

Europe

  • Define and evolve the architecture and roadmap for enterprise‑scale Data and AI platforms.
  • Design and build multi‑tenant, multi‑region, highly available AI platforms with governance.
  • Lead capacity planning and cost optimization strategies for GPU and CPU workloads.

NEORIS accelerates growth in Ibero‑America, combining global engineering with regional expertise. With over 60,000 professionals across 55+ countries, they offer technical specialization career paths and value responsibility, collaboration, creativity, and commitment.

US Global

  • Define end-to-end architecture for AI/ML and Gen AI systems.
  • Serve as a strategic advisor to clients, leading solution design discussions.
  • Architect scalable solutions using cloud-native AI tools.

3Pillar Global provides a flexible work environment with a remote-first approach, offering opportunities for global teamwork and leveraging diverse resources. They focus on well-being, career growth, and diversity.

Ireland 5w PTO

  • Craft and position solutions to help enterprise clients unlock value through applied AI.
  • Lead discovery and pre-sales engagements, crafting proposals and pitches.
  • Translate client objectives into actionable solution roadmaps.

Nearform is an independent team of data & AI experts, engineers, and designers building intelligent digital solutions. They have a collaborative, people-first approach, enabling enterprises to build breakthrough products and modernise legacy systems by unleashing the power of AI; they have 500 experts in 20+ countries.

US

  • Enhance the security of cloud infrastructure.
  • Ensure the protection of patient data and all of the technology behind our platform.
  • Work helps ensure the best outcomes for patients as we strive to make mental healthcare work for everyone.

Rula strives to create a world where mental health is embraced as part of overall well-being. They are dedicated to providing quality, evidence-based care and making a positive impact on the lives of individuals struggling with mental health issues.

US 8w paternity

  • Build and deploy AI-enabled tools, workflows, and internal automations that improve productivity.
  • Connect AI agents, tools, and automations with enterprise systems, ensuring reliable interoperability.
  • Build, maintain, and improve MCP connections and supporting infrastructure.

Openly is rebuilding insurance from the ground up, re-envisioning and enhancing every aspect of the customer experience. They are a rapidly growing team of exceptional, curious, empathetic people with a wide range of skill sets.

$0–$0/yr
US Canada

  • Design, build, and ship agentic workflows across multiple domains.
  • Build multi-step agents capable of autonomous planning, context tracking, memory, tool use, and API orchestration.
  • Drive technical and architectural decisions to meet product requirements while also anticipating and designing for future needs

Cority helps customers see and prevent risks across their operations in real time. Our EHS+ platform converges people, data, and AI agents to provide a clear view of information people can trust. For 40 years, Cority has been the market leader in EHS+, recognized by top analysts and trusted by more than 1,500 of the most complex organizations worldwide.

$125,000–$175,000/yr
US Unlimited PTO

  • Act as a trusted advisor to customers, building relationships with technical and business stakeholders.
  • Advise on GenAI and ML best practices, giving product demos to technical and business stakeholders.
  • Partner with product and engineering teams to drive the product roadmap and spearhead new opportunities within existing accounts.

Arize AI is transforming the world by helping teams monitor, troubleshoot, and optimize their AI systems with its AI & Agent Engineering observability and evaluation platform. They are a Series C company backed by top-tier investors, with over $135M in funding and a rapidly growing customer base.

$25–$25/hr
US

  • Focus on the AI logic required to convert unstructured call summarizations into high-quality, clinical-grade SOAP notes.
  • Help build Arine's prompt generation, defining guardrails and determining how the agent should respond to questions.
  • Ensure complex, human-aware AI engagement that understands patient sentiment and care gaps in real-time.

Arine is a healthcare technology and clinical services company with a mission to ensure individuals receive the safest and most effective treatments for their unique healthcare needs. They are backed by leading healthcare investors, managing more than 18 million lives across prominent health plans and ranked 236 on the 2024 Inc. 5000 list.

US

  • Design, build, and maintain production-grade AI systems and customer-facing AI features.
  • Develop agentic workflows using LLMs, retrieval systems, tools, APIs, and backend services.
  • Design and implement retrieval-augmented generation (RAG) systems, including ingestion pipelines, embeddings, semantic retrieval, and context assembly.

Givzey is a fast-growing and innovative technology company serving the nonprofit sector, on a mission to unlock more generosity through AI-powered donor engagement. In just three years, Givzey’s platform has already helped organizations raise $10M+ through autonomous engagement.

$90,000–$150,000/yr
US

  • Design and deliver production AI and agentic systems across document intelligence, workflow automation, and copilots.
  • Define architecture decisions for LLM-based systems, including retrieval, tool use, orchestration, memory, and evaluation.
  • Own evals and observability for production AI and manage cost and latency at production volume.

Maxwell is a mortgage technology and fulfillment company with a mission to make lending simpler, faster, and more accessible. They power hundreds of lending institutions with their mortgage Point of Sale and related capabilities and are a remote-first team that takes craft seriously.