Source Job

$100,000–$140,000/yr
US 3w PTO

  • Lead and oversee complex clinical trial operations from initiation through closeout.
  • Serve as primary operational contact for industry-sponsored trials, ensuring quality and compliance.
  • Mentor clinical operations managers and drive process improvements across projects.

Clinical Research Project Management GCP Vendor Management Microsoft Office

20 jobs similar to Senior Clinical Trial Operations Manager

Jobs ranked by similarity.

$155,000–$195,000/yr
North America

  • Support planning and operational execution of clinical trials, coordinating across sites, CROs, vendors, and teams.
  • Manage vendor oversight, budgets, timelines, risks, and documentation ensuring GCP compliance.
  • Serve as primary operational contact and mentor junior staff for global Phase 1-3 trials.

Jade Biosciences is a clinical-stage biotechnology company developing best-in-class therapies for autoimmune diseases. It is a small, dynamic company offering an exciting opportunity to contribute to its immunology pipeline.

US Unlimited PTO

  • Collaborate with the Clinical Operations team to support timely conduct of clinical studies according to protocols, GCP, SOPs, and regulations.
  • Lead operational management for assigned regions and sites, including vendor management and oversight of CRO monitors.
  • Contribute to the development and maintenance of study documents and ensure the Trial Master File is complete and inspection-ready.

BridgeBio is a biopharmaceutical company founded to discover, create, test, and deliver transformative medicines for patients with genetic diseases and cancers with clear genetic drivers. Founded in 2015, the company has built a portfolio of 20+ drug development programs spanning preclinical to late-stage development across multiple therapeutic areas.

$95,500–$159,000/yr
North America

  • Lead clinical research project planning, execution, and delivery, ensuring regulatory compliance and quality.
  • Coordinate cross-functional teams and manage timelines, budgets, and study documentation.
  • Serve as the primary sponsor and client contact, providing regular project updates and resolving issues.

Alimentiv is a global CRO advancing therapies for gastrointestinal diseases, with deep expertise in IBD drug development. With about 700 employees across multiple countries, it is a private, profit-with-purpose company focused on scientific research and its people.

$130,000–$190,000/yr
US Unlimited PTO

  • Manage all clinical operational aspects of global trials including start-up, conduct, and close-out.
  • Oversee CRO and site adherence to GCP and SOPs, proactively identifying and resolving study risks.
  • Lead study team meetings, build investigator relationships, and support protocol development.

Vera Therapeutics is a commercial-stage biotech focused on transforming autoimmune disease treatment, starting with the kidney. Founded in 2016 in Brisbane, CA, the company values empathy, ownership, clarity, and urgency in a collaborative, fast-paced team.

EMEA

  • Lead Clinical Trial Liaison performance, development planning, and quality delivery across EMEA.
  • Oversee vendor-provided staff, implement standardised feasibility and site selection processes, and build investigator relationships.
  • Report monthly metrics, escalations, and best practices while retaining a 15% liaison workload.

Regeneron is a leading biotechnology company that invents life-transforming medicines for people with serious diseases. Founded and led for over 30 years by physician-scientists, the company has a culture of innovation and has been recognized as a Great Place to Work.

$85,000–$115,000/yr
US

  • Support Clinical Trial Managers with study start-up, protocol development, and Trial Master File preparation.
  • Coordinate with clinical sites on documentation, training, and compliance with FDA and GCP requirements.
  • Assist with tracking study payments and providing operational support across the full study lifecycle.

The company is a partner organization specializing in clinical research and development, operating through Jobgether. It offers a structured clinical operations environment with cross-functional teams and professional growth opportunities.

$162,000–$243,000/yr
US

  • Serve as primary point-of-contact liaison with clients and oversee all aspects of clinical trials.
  • Manage study budgets, project timelines, risk, and cross-functional teams to ensure quality and compliance.
  • Drive bid defense preparation, client presentations, and continuous process improvement across assigned portfolios.

Precision for Medicine supports clinical research and development for biopharmaceutical and life science companies. It is a global, collaborative organization that emphasizes quality, innovation, and professional growth.

Global

  • Lead and oversee global Phase 0-4 clinical trials with cross-functional teams from inception to closure.
  • Manage external vendors, recruitment strategies, and study systems to ensure quality, efficiency, and inspection readiness.
  • Collaborate with study project managers to drive timelines, budgets, and compliance with ICH/GCP and AbbVie policies.

AbbVie discovers and delivers innovative medicines and solutions across immunology, oncology, neuroscience, and Allergan Aesthetics. They are a global, science-driven pharmaceutical company committed to integrity, innovation, and serving the community.

India

  • Lead medium- to high-complexity clinical trials with full accountability for timelines, budgets, resources, and quality.
  • Oversee financial performance, risk mitigation, and quality standards while ensuring regulatory compliance.
  • Mentor Project Leaders and represent project leadership in client meetings, bid activities, and conferences.

A clinical research organization managing complex clinical trials and therapies. It fosters a fast-paced, collaborative environment focused on innovation, accountability, and professional development.

$158,000–$188,000/yr
US

  • Serve as scientific lead for clinical programs, supporting trial design, execution, data interpretation, and regulatory activities.
  • Collaborate with cross-functional teams including Clinical Operations, Biostatistics, Regulatory Affairs, and external partners.
  • Contribute to scientific publications, regulatory submissions, and relationships with investigators and key opinion leaders.

The company is a clinical-stage organization advancing innovative regenerative therapies for significant unmet needs in ophthalmology. It fosters a collaborative, high-performance culture with mentorship and professional growth opportunities.

$115,000–$135,000/yr
US Europe

  • Lead and coach a team of Clinical Study Operations professionals overseeing device-based clinical trials from feasibility to close-out.
  • Drive domain-level ClinOps initiatives including process standardization, tooling, and data quality improvements.
  • Represent ClinOps in business development conversations, feasibility discussions, and Investigator Meetings, ensuring operational readiness.

Beacon Biosignals transforms precision medicine for the brain, offering at-home EEG and diagnostic platforms for neurological, psychiatric, and sleep disorders. They are a remote-first, distributed company with hubs in Boston, New York, and Paris, emphasizing curiosity, sound judgment, and empathy.

US

  • Build and strengthen strategic partnerships with clinical research sites and site organizations across an assigned region and therapeutic area.
  • Act as an enterprise-level partner engaging senior executives and C-suite stakeholders to establish durable, mutually beneficial relationships.
  • Drive improved clinical trial execution through collaboration, reduced startup timelines, and measurable quality standards.

The company is a healthcare organization focused on improving clinical trial execution through strategic partnerships with research sites. It fosters a collaborative and inclusive environment supporting leadership development and meaningful impact on patient outcomes.

US

  • Collaborate with project teams to support study startup and serve as primary point of contact for clinical sites.
  • Provide training on Beacon's devices and protocols, monitor progress, and maintain GCP/ICH compliance.
  • Address operational issues via Zendesk and Asana and deliver actionable site feedback for workflow improvements.

Beacon Biosignals is transforming precision medicine for the brain with at-home EEG and cardiopulmonary monitoring platforms for clinical development and diagnostics. They foster a remote-first culture with hubs in Boston, New York, and Paris, emphasizing curiosity, simplicity, and empathy.

US

  • Direct and manage a team of Project Directors and Project Managers in global project delivery.
  • Provide leadership and oversight for clinical programs and act as primary escalation point for sponsors.
  • Optimize profitability, manage resources, and ensure compliance with quality standards and regulations.

Precision Medicine Group provides clinical research and project management services for global clinical trials. The company promotes a culture centered on quality, people, clients, and performance.

$90,000–$110,000/yr
US

  • Lead planning, execution, and integrated governance for Future of Medicine initiatives across Clinical Conduct, Quality, Technology, and Operations.
  • Translate clinical, operational, quality, and program needs into scalable workflows, requirements, SOPs, and training.
  • Drive readiness, change planning, and sustained adoption of new program requirements and technology capabilities.

Care Access brings world-class clinical research and health services to communities facing barriers to care through hundreds of research locations, mobile clinics, and global clinicians. The company values an inclusive culture where diverse backgrounds are welcomed and people are at the heart of medical progress.

$137,300–$242,300/yr
US

  • Lead clinical study strategy and execution for regulatory approvals and evidence initiatives.
  • Partner with stakeholders, investigators, and KOLs to design protocols and manage study progress.
  • Oversee monitoring, compliance, and data analysis while mentoring junior staff.

Intuitive is a global leader in robotic-assisted surgery and minimally invasive care, known for da Vinci and Ion systems. Its team of engineers, clinicians, and innovators works to make surgery smarter, safer, and more human.

Poland

  • Lead full service clinical projects in Oncology, ensuring timelines, budget, and quality.
  • Serve as primary client liaison and coordinate cross-functional teams across all study stages.
  • Manage all aspects of clinical trials, including proposal strategy, documentation, and reporting.

Precision for Medicine is a CRO enabling precision medicine through novel clinical trial designs, biomarker and data analytics, and a focus on rare diseases and oncology. We are a supportive, collaborative team that values work life balance and development.

Latin America

  • Lead planning, execution, and oversight of clinical studies across Latin America.
  • Act as primary client contact and ensure compliance with ICH-GCP, SOPs, and regulatory requirements.
  • Mentor CRAs and partners while shaping country-level recruitment and monitoring strategies.

Precision Medicine Group provides clinical development, regulatory, and commercial solutions for life sciences companies. It fosters a collaborative, high-integrity culture with opportunities for growth and leadership in a global remote environment.

$80,000–$110,000/yr
US

  • Manage administrative and scheduling support for the CareMind Inpatient practice, including provider onboarding, training, and credentialing.
  • Develop staffing models, create 90-day schedules, and coordinate with payroll for accurate provider pay.
  • Track provider PTO, oversee FPPE/OPPE reviews, and ensure performance against outcome measures.

CareMind Health is a captive clinical services entity of Mindoula Health and a national provider of virtual psychiatry and behavioral health care. We are a patient-centered team focused on supporting mental health and delivering comprehensive solutions for hospitals and partners.

Global

  • Partner with Clinical Scientists and Clinician Services leaders to design and deliver study-specific training programs.
  • Develop calibration strategies, monitor clinician performance, and implement quality improvements.
  • Lead group training, coaching, and documentation while ensuring GCP and regulatory compliance.

Clario, part of Thermo Fisher Scientific, provides endpoint data solutions for clinical trials. Its global team has supported over 30,000 clinical trials and 70% of FDA drug approvals since 2015.