Source Job

US

  • Lead the reference architecture for AI and agentic systems within key product domains.
  • Design and deliver production ready AI systems, ensuring reliability, scalability, observability, performance, and cost efficiency across the full lifecycle.
  • Establish platform level AI and data components, including Model broker and multi-model routing strategies.

AI Data LangChain LangGraph

20 jobs similar to Principal Software Engineer (AI)

Jobs ranked by similarity.

$170,000–$200,000/yr
US Unlimited PTO

  • Contribute to the design and evolution of agentic systems that participate directly in care delivery.
  • Define and build architectural patterns for agent reasoning, tool use, memory, and human-in-the-loop collaboration.
  • Own complex problem spaces end-to-end — from system design and implementation through observability, evaluation, and continuous improvement in production.

Pair Team is building a new kind of healthcare system across Medicaid, Medicare, and public assistance programs. As a public benefit corporation and AI-enabled medical group, they partner with shelters, food pantries, and community organizations to deliver “whole-person” care to the 115 million Americans who rely on the safety net, employing over 500 people while expanding nationally.

US Unlimited PTO

  • Architect and deploy autonomous AI agents and multi-agent workflows.
  • Design strict-source-following Retrieval-Augmented Generation (RAG) systems.
  • Build scalable backend services using FastAPI.

Osano is an innovative B-Corporation focused on giving modern enterprises the ability to innovate quickly and earn customer trust by respecting data privacy and complying with consent guidelines. We are scaling fast with a multi-year runway and ambitious growth plans.

$111,888–$128,633/yr
Canada US

  • Design and build production-grade AI systems, including RAG pipelines, multi-step agents, and LLM-powered features.
  • Build comprehensive evaluation and observability frameworks to measure model accuracy, grounding, and quality drift.
  • Create production-quality Python services to wrap AI logic into secure microservices.

League, founded in 2014, is the leading healthcare consumer experience (CX) platform powered by AI, reaching over 63 million people globally. Payers, providers, and consumer health partners use League’s platform to deliver high-engagement healthcare solutions and improve health outcomes.

$179,400–$250,000/yr
US

  • Lead development and delivery of scalable software systems supporting AI models.
  • Shape AI architecture from high-level vision to robust implementation.
  • Manage a small team of senior software engineers in a player/coach model.

Headspace offers access to lifelong mental health support, combining evidence-based content, clinical care, and innovative technology. Their values shape decisions, guide collaborations, and define their culture, building a more connected, human-centered team.

India 7w PTO

  • Design and implement production-scale AI agent systems and orchestration frameworks.
  • Deploy and optimize LLMs/SLMs in production with fine-tuning techniques.
  • Build data pipelines for training data curation, synthetic generation, and PII masking.

FourKites is the leader in AI-driven supply chain transformation for global enterprises and a pioneer of advanced real-time visibility. They turn supply chain data into automated action helping 1,600+ global brands prevent disruptions. They provide competitive compensation with stock options, outstanding benefits and a collaborative culture for all employees around the globe.

US

  • You will define, build, and evolve foundational systems that enable autonomous agents to operate reliably in production.
  • You’ll explore new approaches, prototype quickly, and turn what works into durable platform foundations.
  • You’ll identify high-leverage architectural improvements, abstractions, and guardrails that expand what the platform can do while keeping it reliable, secure, observable, and maintainable under real-world conditions.

Kindo is an agent automation platform for DevOps and SecOps teams, helping organizations automate high-friction operational work using autonomous agents. They are a small, highly technical team with strong customer traction and real enterprise revenue, where engineers have direct ownership over critical systems.

$204,500–$290,000/yr
US

  • Serve as the primary AI engineering partner to the CEO and executive leadership team, translating ideas into production-ready AI agents.
  • Independently take ideas from concept to production, shaping problem statements and operationalizing solutions.
  • Develop production-grade AI systems using modern LLMs, with strong attention to scalability and clean engineering practices.

Webflow is building the world’s leading AI-native Digital Experience Platform as a remote-first company. Their mission is to bring development superpowers to everyone and empower teams to design, launch, and optimize for the web without barriers.

US

  • You will design, build, and operate core systems that enable autonomous agents to function reliably in production.
  • You’ll build production-grade agentic workflows, retrieval and memory systems, multi-model execution, and tool-calling integrations that interact safely with enterprise systems.
  • You’ll explore new approaches, prototype quickly, and turn what works into durable production systems.

Kindo is an agent automation platform for DevOps and SecOps teams. They help organizations automate high-friction operational work using autonomous agents. Kindo is a small, highly technical team with strong customer traction and real enterprise revenue.

$140,000–$160,000/yr
US 4w PTO

  • Design and build agentic AI systems and RAG pipelines for production features across the marketplace.
  • Integrate LLMs into product experiences across search, categorization, communication, and trust & safety.
  • Partner with Data Scientists and Engineers to turn research into shipped products.

OfferUp is dedicated to creating the simplest and most trusted way for people to buy, sell, and connect in their local communities. OfferUp used by more than 1 in 6 adults in the U.S. in 2024.

$88,911–$117,952/yr
Canada

  • Build AI-Powered Features: Design, develop, and deploy production-grade AI applications from concept to deployment.
  • Architect Scalable Systems: Create robust backend architectures that support AI workloads, ensuring low latency and high reliability.
  • Drive AI Innovation: Implement and optimize agentic AI systems, RAG pipelines, and multi-agent workflows using modern LLM frameworks.

Procurify is the AI-enhanced procurement and AP automation platform for mid-market organizations, making it easy for organizations to take control of spending and save money. It is a remote-first company with a big heart and a strong ambition to modernize how organizations manage business spend.

  • Act as a "scouter" for the executive team, taking high-level goals and executing them from start to finish.
  • Personally design, configure, and deploy AI agents and automated workflows using systems such as Microsoft Copilot Studio or Power Automate.
  • Train staff on the tools you build and iterate based on their direct feedback.

Ennoble Care is a mobile primary care, palliative care, and hospice service provider with patients in multiple states. They provide continuum of care for those with chronic conditions and limited mobility, striving to provide the highest quality of care by a team patients know and trust.

AI Engineer

M3 USA
US

  • Build AI-powered systems to automate and improve workflows.
  • Work closely with business teams to understand processes and pain points.
  • Use AI coding agents to build software more rapidly than traditional methods.

M3 USA delivers digital solutions to healthcare, life sciences, and pharmaceutical industries. They focus on physician communities globally and have a dynamic, innovative work environment.

$165,000–$185,000/yr
US 4w paternity

  • Design and implement infrastructure to support LLM-based autonomous agents capable of multi-step reasoning, planning, and task execution.
  • Architect and maintain cloud-native platforms that support end-to-end AI workflows, from model experimentation to high-availability production deployment.
  • Implement security controls against prompt injection and ensure PII/PHI de-identification within agentic data flows.

Lirio is a technology/software company that provides expertise in a variety of behavioral science domains, data science, and machine learning to drive consumer engagement, close gaps in preventive and chronic care, and promote health and well-being. They are using a behavior change AI platform to deliver Precision Nudging health interventions.

US Unlimited PTO

  • Rapidly prototype MVPs using LLM APIs to address business bottlenecks.
  • Develop production-grade internal applications with reliable frontends and robust backends (Python).
  • Design and implement RAG architectures and structured output pipelines grounded in company data.

Bestow is a leading vertical technology platform that serves some of the largest and most innovative life insurers. Their platform unifies the fragmented, legacy value chain, enabling carriers to launch products in weeks instead of years. They are backed by leading investors and trusted by major carriers.

$130,000–$140,000/yr
US

  • Define technical direction and architecture for AI-powered features.
  • Build end-to-end AI solutions, from exploring models and APIs to designing data flows.
  • Act as a multiplier for other teams by pairing with engineers and sharing best practices.

Panopto is a customer-centric learning technology company and the leader in visual and audio-based learning. They empower organizations to share knowledge effortlessly and have been adopted by more than 1,600 companies and universities worldwide with over 11 million end users.

$164,523–$164,523/yr
5w PTO

  • Ship flagship agentic capabilities: Deliver high-impact agentic workflows end-to-end.
  • Build and operate production-grade agent systems: Design reliable agentic systems that behave predictably under real-world constraints.
  • Create shared foundations for agent delivery: Develop the core primitives that enable teams to build agents consistently.

They are rebuilding the energy transaction, making it transparent and fair. Tem exists to fix a broken global energy market and is scaling internationally. The company has closed a $75 million Series B and has facilitated thousands of business customers.

Global

  • Design and develop AI-powered developer tools using Claude-based technologies.
  • Build intelligent agents and automated workflows that improve SDLC efficiency.
  • Develop and orchestrate multi-agent systems using modern agentic frameworks.

Ubiminds is a GPTW-certified, people-first company that partners with American software product companies to scale their global teams. They connect top LATAM talent with international product companies while providing full employer-of-record support and long-term career development.

Global 4w PTO

  • Lead AI-driven transformation of internal processes across the company
  • Design and implement LLM-based agent pipelines, including multi-agent systems
  • Build and maintain RAG architectures

Ideals is a global B2B SaaS product company recognized as the most highly rated and customer-centric brand in the secure business collaboration market. They are trusted by over 2,000,000 users from 300,000 companies globally, helping people run high-stakes processes and make important decisions.

Europe 5w PTO

  • Lead Through Code, solving patient engagement challenges using AI tools like GitHub Copilot.
  • Pioneer new AI-enabled development cycles, scaling successful approaches across engineering.
  • Partner with Product and Design to solve patient problems and measure the impact of new approaches.

Docplanner connects patients with doctors, integrating smart tools for quicker diagnoses and treatments. They operate in 13 countries with over 2,500 employees, maintaining a startup-mindset and a diverse group of over 300 people in Engineering, Data, and Product teams.

Europe

  • Build and ship AI-powered product and internal solutions using LLMs, RAG, tool calling, workflows, and agentic patterns
  • Design quality and evaluation frameworks for AI systems, including offline evals, online signals, failure analysis, and continuous improvement loops
  • Contribute to AI platform and tooling decisions that improve reuse, speed, and consistency across teams

Finom is a European tech startup headquartered in Amsterdam, revolutionizing financial landscape for entrepreneurs. They develop an all-in-one financial B2B solution integrating banking, accounting, financial management, and invoicing into a mobile-first platform and nurture innovation in an inspiring work environment.