Source Job

US 4w PTO

  • Build and ship AI methods for federal research data with LLMs, NLP, RAG, knowledge graphs.
  • Benchmark AI against baselines and human reviewers to prove gains in accuracy, reliability, efficiency, cost.
  • Set standards for trustworthy AI and mentor data scientists through code review and guidance.

Python Machine Learning LLMs RAG

20 jobs similar to Lead Applied AI Scientist

Jobs ranked by similarity.

$250,000–$300,000/yr
US Canada Unlimited PTO

  • Own the build out of new agents, skills, and platform capability for teams across TLDR.
  • Build and deploy agents end to end, from design through implementation, evals, and rollout to internal users.
  • Partner with stakeholders across sales, editorial, and people ops to find where an LLM belongs in their process.

TLDR runs the largest network of tech newsletters in the world, with over 8 million subscribers covering startups, software engineering, AI, and more. Our 31-person full-time team is bootstrapped, profitable, and on track for $35M in revenue this year, with a culture of owning functions rather than slices.

US

  • Design and optimize RAG solutions combining LLMs with enterprise knowledge stores.
  • Build AI knowledge architectures, reusable agents, and copilots for analytical workflows.
  • Collaborate with engineering teams to deploy AI capabilities across business applications.

This company provides AI-enabled analytics solutions for enterprise customers, leveraging generative AI, machine learning, and modern data platforms. It fosters a collaborative, cross-functional culture with career progression opportunities and exposure to emerging AI technologies.

  • Design, build, and operate LLM-powered applications and services over catalog, sales, and operational data.
  • Stand up and maintain MCP servers and tool integrations that connect AI models to internal systems.
  • Own services end-to-end, evaluate emerging AI tooling, and raise the team's AI engineering capability.

Penguin Random House is the leading adult and children's publishing house in North America, the United Kingdom and many other regions around the world. We are committed to quality, excellence, and innovation throughout the entire publishing process, with a vibrant and diverse international community of nearly 300 publishing brands and imprints.

$130,000–$200,000/yr
US

  • Develop and improve AI methods, algorithms, and systems across the lifecycle of reliable AI agents.
  • Create new approaches for simulating, evaluating, and optimizing agent behavior in real-world settings.
  • Turn research ideas into working systems, prototypes, and production-facing capabilities.

The company builds infrastructure that helps enterprises make AI agents more reliable in production. It is a technical and research-focused team working on AI methods and practical systems.

US

  • Define end-to-end requirements for AI capabilities, from model behavior to user experience.
  • Translate model capabilities and technical constraints into product decisions.
  • Work closely with ML and engineering teams on system design and iteration.

They develop AI-powered email applications and work at the intersection of user needs and model capability. The company is fast-moving and collaborative with a strong focus on technical ownership and innovation.

$130,000–$200,000/yr
US

  • Develop and improve core AI methods and systems for reliable AI agents across the full lifecycle.
  • Create novel approaches for simulation, evaluation, and optimization of agent behavior in production.
  • Turn research ideas into working prototypes and production-facing capabilities.

This is an early-stage AI infrastructure company focused on making AI agents reliable in production. The company values innovation and practical deployment, with a small team driving frontier AI research and product development.

$160,000–$185,000/yr
United States

  • Conduct independent research in Generative AI, LLMs, NLP, and multimodal AI to design experiments and evaluate models.
  • Develop and implement LLM evaluation frameworks, analyze model performance, and identify data gaps for improvement.
  • Apply strong statistical and data science skills to clean, analyze, and interpret complex datasets for AI/ML research.

Innodata is a global data engineering company that enables the responsible advancement of artificial intelligence by providing data, evaluation frameworks, and human expertise. With a 36+ year legacy, the company is committed to delivering the highest quality data and outstanding outcomes for its customers.

Global

  • Design and implement autonomous agents and multi-agent orchestration systems for complex, open-ended tasks.\n- Build and optimize production-grade LLM applications with a focus on reliability, observability, and low-latency performance.\n- Architect advanced RAG pipelines and vector database strategies to provide agents with accurate, real-time context.

Jobgether is an AI-powered job matching platform that connects candidates with hiring companies through objective evaluation. The company operates with a distributed, global-first team culture, emphasizing fairness and innovation in recruitment.

US Unlimited PTO

  • Build the component layer around our layout synthesis engine, including API contracts, services, and evaluation gates.
  • Turn model retraining into a one-command job with built-in benchmarks and readable results for the whole team.
  • Own latency and cost budgets for learned capabilities and partner with infrastructure engineers on MLOps and deployment.

Higharc is a VC-backed startup that is changing how new homes are designed and built using spatial AI and generative floor plan technology. The company is fully remote, has raised over $175M, and values flexibility, collaboration, and asynchronous deep work.

US

  • Collaborate with client teams to diagnose operational bottlenecks and develop testable hypotheses.
  • Build and test AI-powered prototypes using coding agents like Claude Code or Cursor.
  • Drive adoption by working directly with users and iterating on solutions until they are effective in live workflows.

Jobgether is an AI-powered job matching platform that connects candidates with hiring companies. The platform uses AI to review applications and provide a shortlist to employers, emphasizing efficiency and objectivity.

$200,000–$350,000/yr
US Unlimited PTO

  • Architect, build, and optimize high-performance production LLM systems while maintaining a strong personal technical presence on the team.
  • Spearhead strategic technological changes and champion code refactoring efforts to keep the core codebase cutting-edge and performant.
  • Lead technical story breakdowns, architectural design, and mentor engineers across the department.

Appian provides AI automation for mission-critical work, automating complex processes in large enterprises and governments. With over 25 years of experience, the company is known for its reliability and scale, and fosters an inclusive culture with employee-led affinity groups.

$170,144–$230,000/yr
US

  • Assess current-state service desk and contact center environments and design future-state support models leveraging AI, automation, and intelligent assistance.
  • Develop modernization strategies, business cases, and ROI models that demonstrate measurable cost savings and operational improvements.
  • Lead discovery sessions, prototype AI solutions, and support business development through proposals and executive presentations.

Our partner applies AI, machine learning, automation, and analytics to modernize customer and employee support environments for government and commercial clients. They offer a collaborative, innovation-focused environment with opportunities to work alongside experienced technical and mission-focused professionals.

US

  • Lead end-to-end delivery of complex healthcare AI products, including agentic workflows, RAG systems, and production services.
  • Collaborate with Product, Engineering, Data, and clinical teams to translate stakeholder needs into validated, access-aware AI workflows.
  • Own evaluation frameworks, model optimization, and human-review controls to keep high-stakes workflows safe, reliable, and governable.

NeueHealth is a value-driven healthcare company that aligns the interests of health consumers, providers, and payors to make healthcare accessible and affordable. They deliver clinical care through owned clinics and provider partnerships while enabling performance-based care with technology and services.

US

  • Partner with product managers, engineers, and operations leads to build AI-powered tools.
  • Design and operate an evaluation framework to ensure AI tools meet quality standards.
  • Own the repository health, governance model, and responsible AI practices.

Maleda Tech is a technology staffing firm that connects professionals with contract opportunities. The company culture is not described in the posting.

$120,000–$225,000/yr
US 4w PTO

  • Design, fine-tune, and deploy language model-based solutions from research to production.
  • Build and improve GenAI pipelines including RAG, corrective RAG, and agentic orchestration.
  • Develop scalable data and embedding pipelines, and evaluate generative AI outputs against accuracy and safety standards.

Liberty Mutual is a global insurance company that builds generative AI capabilities for its products. It is a large organization with an inclusive culture that values diverse perspectives, flexibility, and professional development.

$230,000–$322,000/yr
US

  • Lead the development and optimization of machine learning models to detect and prevent AI security risks like prompt injection and jailbreaks.
  • Build reproducible training and evaluation pipelines on Reddit's ML platform, partnering with platform engineers to improve performance and reliability.
  • Set the technical vision and multi-quarter modeling roadmap, mentoring engineers and establishing best practices for responsible ML development.

Reddit is a community of communities, built on shared interests and authentic conversations, with 100,000+ active communities and 130 million daily active visitors. It is one of the internet's largest sources of information, fostering a culture of openness and trust.

Global

  • Develop and deploy cutting-edge AI/ML solutions to enhance the platform and improve student learning experiences.
  • Design, develop, and optimize LLM-powered agentic systems and APIs for real product use cases.
  • Collaborate with senior engineers and contribute to evaluation frameworks and MLOps pipelines.

Interview Kickstart specializes in interview preparation and career transitions into high-demand tech fields like AI, ML, and Data Science. Over 17,000 tech professionals have been guided by current and former hiring managers to land coveted positions at companies like Google and Amazon.

$103,000–$117,000/yr
Canada Unlimited PTO

  • Design, build, and deploy LLM-powered product features, including lab summaries and conversational agents.
  • Build backend services integrating LLMs and ML models, primarily using Python with exposure to Elixir.
  • Implement evaluation, monitoring, and CI/CD workflows for AI features, ensuring reliability and clinical relevance.

Fullscript is a health technology platform that helps practitioners deliver better care through clinical insights, lab interpretations, and patient analytics. With over 125,000 practitioners and 10 million patients, the company emphasizes a people-first culture, teamwork, and continuous learning in a remote-first environment.

$105,000–$147,000/yr
US

  • Build and ship features of AI/ML and LLM-powered systems with guidance from senior engineers.
  • Implement and maintain AI/ML and AI agent pipelines from data ingestion through model deployment.
  • Contribute to LLM-powered features such as prompts, evaluations, retrieval, and tool integrations, while documenting experiments clearly.

Robots & Pencils designs AI systems for a human world, pairing engineering with creativity. Teams average fifteen-plus years of experience and value ownership, craft, direct feedback, and continuous learning.

North America

  • Design and build production-grade AI agentic systems for web and chat experiences.
  • Architect agent workflows involving reasoning, tool use, retrieval, guardrails, and monitoring.
  • Build LLM evaluation systems and diagnose agent performance issues across prompts and tools.

Netomi is an agentic AI platform for enterprise customer experience, enabling automation for global brands. Backed by Y Combinator and Index Ventures, the company drives efficiency and higher quality experiences.