Remote Software engineering Jobs · Python

Job listings

$248,000–$341,000/yr

  • Lead a full-stack team of engineers building and operating Discord's notification platform, including Elixir services, Python backends, and Kubernetes infrastructure.
  • Set technical direction for notifications infrastructure and ensure systems scale reliably as volume and complexity grow.
  • Partner with Product, Design, Data Science, and Marketing to define the notifications roadmap and drive improvement through experimentation and metrics.

Discord is a multiplatform, multigenerational, and multiplayer platform that helps people deepen friendships around games and shared interests. It has a highly engaged community of millions of daily active users and is focused on making gaming easier and more fun.

$175,000–$250,000/yr
US Unlimited PTO

  • Own the intelligence layer of Project Interstellar, building production LLM systems for document intelligence, voice agents, and task orchestration.
  • Design and maintain prompt engineering infrastructure, model abstraction, RAG layers, and agent orchestration frameworks.
  • Partner with engineering and domain experts to integrate AI capabilities into a HIPAA-regulated platform from the ground up.

Certum Legal Solutions is a legal managed services organization that provides operational infrastructure, technology, and back-office solutions for personal injury law firms. The company is building a proprietary AI-native system and is assembling a high-caliber team in a greenfield, fast-paced environment.

US Unlimited PTO

  • Build and maintain AI agents using large language models to complete multi-step tasks within Cayuse products.
  • Develop and extend MCP servers and integrate AI features into existing applications through platform APIs.
  • Write unit and integration tests, participate in code reviews, and ship code through CI/CD pipelines.

Cayuse provides integrated technology solutions that empower organizations to conduct globally connected research, advancing impact in science and discovery. The company is a team of highly skilled, multidisciplinary professionals building a remote-first culture with a focus on customer and employee values.

Canada Unlimited PTO

  • Own and deliver quarterly goals, leading engineers through ambiguity and ensuring support.
  • Collaborate with product, design, and analytics to make decisions considering risks and trade-offs.
  • Support operations and availability of team artifacts while fostering quality and ownership.

Affirm provides clear, predictable buy now, pay later services with no hidden fees. It is a growing, remote-first company that values transparency, flexibility, and customer trust.

$180,000–$240,000/yr

  • Design and improve AI systems for extracting structured reasoning signals from technical interviews.
  • Build LLM-powered pipelines for semantic analysis, behavioral feature extraction, and evaluation.
  • Develop scoring, calibration, and benchmarking methods grounded in measurable evidence.

APADCode is an early-stage AI startup building an AI-powered technical interview platform that evaluates how candidates reason and solve problems. The company is a small, early-stage team with a culture of high ownership, direct collaboration, and minimal bureaucracy.

  • Distributed pretraining: Implement and optimize model-parallel training on heterogeneous GPUs under low-bandwidth, high-latency links.
  • Performance optimization: Apply techniques that reduce communication overhead while maintaining model convergence in challenging network environments.
  • Elasticity and fault tolerance: Build robust checkpointing and recovery so runs survive node churn as participants join and leave.

Pluralis Research is a decentralized AI research company developing Protocol Learning to train large models on consumer devices across the internet. The team is world-class and deeply technical, backed by tier-1 investors, with a remote-first culture.

Global 6w PTO 26w maternity 26w paternity

  • Work with a small, talented team to craft delightful user-facing experiences on the Cohere Dashboard.
  • Build resilient, mission-critical systems across browsers and servers using Next.js, TypeScript, React, and Python.
  • Collaborate with engineering colleagues through pairing, architecture design, and documentation to increase velocity.

Cohere is a security-first enterprise AI company that builds cutting-edge foundation models and end-to-end products for businesses. It is a global team of researchers, engineers, and designers passionate about their craft, with offices in Toronto, London, New York City, San Francisco, Montreal, Paris, Berlin, and Seoul.

$255,000–$290,000/yr

  • Own complex database architecture decisions: schema design, partitioning, migrations, and scalability.
  • Set PostgreSQL standards at scale: query optimization, indexing, replication, and connection pooling.
  • Mentor engineers and partner cross-functionally to define data contracts and architectural guardrails.

Horizon3.ai is a remote cybersecurity company building NodeZero, an autonomous pentesting platform that helps organizations find and fix exploitable attack vectors. It's a fast-growing team of former special ops cyber operators and engineers, with a culture of respect, collaboration, ownership, and results.

  • Develop and maintain web-based software for biomedical data discovery and visualization.
  • Integrate a natural-language conversational AI system into biomedical data portals for querying and understanding complex biological data.
  • Participate in the full software development life cycle, including testing, documentation, and code reviews.

Harvard University is a prestigious research university dedicated to education and discovery. Its HIDIVE Lab in Biomedical Informatics develops AI and data visualization tools to help scientists understand complex biomedical data, fostering a collaborative and interdisciplinary culture.

  • Design and build conversational agents and agentic workflows using Microsoft Copilot Studio, Power Automate, and Python.
  • Integrate AI solutions with enterprise data platforms like Snowflake and SharePoint, and operate them on Azure with CI/CD.
  • Set observability standards with Splunk and provide technical leadership across global teams.

Coderio designs and delivers scalable digital solutions for global companies. They are a fully remote company that values autonomy, clear communication, and technical excellence.