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20 jobs similar to Lead Bioinformatician/Engineer (Pipelines and Infrastructure)

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US

  • Own and improve WDL and Nextflow workflows on AWS infrastructure, ensuring pipelines are easy for scientists to run without engineering support.
  • Build and harden internal tooling to reduce manual work, and implement testing, monitoring, and alerting to surface failures early.
  • Partner with science leads and data scientists to get new methods into production, and use coding agents as a routine part of engineering.

Natera is a global leader in cell-free DNA testing, dedicated to oncology, women's health, and organ health. The team consists of highly dedicated statisticians, geneticists, doctors, and software engineers from world-class institutions, working together to change the landscape of genetic disease management.

US

  • Provide genomics algorithm insights for panel design and assay edge cases, working with cross-functional teams.
  • Define computational strategy for new callers, prototype and benchmark methods, and partner with engineering to productionize.
  • Serve as genomics consultant on complex escalations, separating biological causes from analytical ones, and turning investigations into durable rules.

Natera is a global leader in cell-free DNA testing dedicated to oncology, women’s health, and organ health. The team consists of highly dedicated statisticians, geneticists, doctors, and other professionals from world-class institutions, fostering a culture of hard work and growth.

$122,000–$129,200/yr
US Unlimited PTO 16w maternity 4w paternity

  • Build, operate, and scale AWS infrastructure supporting a microservices platform.
  • Develop and maintain CI/CD pipelines to make shipping fast, reliable, and safe.
  • Partner with product engineering teams, translating platform concepts into practical guidance.

Storyblocks is a content company that provides video, audio, images, and creative tools through a subscription model, empowering storytellers. They are a remote-first company with a culture driven by data, empowered communication, and ownership, recognized as a top workplace.

US

  • Develop and maintain core cloud infrastructure using AWS, Terraform, and serverless architecture.
  • Build robust CI/CD pipelines and manage deployment tools for seamless code delivery.
  • Automate routine tasks, improve documentation, and participate in on-call support rotations.

LeanTaaS creates software solutions combining lean principles, predictive analytics, and machine learning to transform hospital and infusion center operations. More than 190 health systems and over 1,200 hospitals rely on their products, and they have raised over $300 million from top-tier investors, being named among the top 100 AI companies.

$108,400–$127,500/yr
US

  • Contribute to active development on the sequencing analysis pipeline in Python, including bug fixes, feature work, and code reviews.
  • Own and maintain CI/CD pipelines, build configuration, and regression infrastructure (Jenkins, Bitbucket, HPC).
  • Respond to inbound triage requests from the field, diagnosing and resolving pipeline failures on sequencing instruments.

Singular Genomics develops genomic sequencing platforms for research and clinical applications. It is a rapidly growing company with a culture of creativity and collaboration.

$100,000–$110,000/yr
US Unlimited PTO 14w maternity 14w paternity

  • Maintain uptime and security of AWS-hosted MERN applications and backend architectures.
  • Manage serverless functions and PySpark data pipelines, triaging incidents and automating workflows.
  • Lead blameless post-mortems and ensure HIPAA compliance across all healthcare data systems.

Cohere Health offers an AI-powered clinical intelligence platform connecting health plans and providers to improve care speed, cost, and quality. Named to the Inc. 5000 list and a top LinkedIn startup, the company is backed by leading investors and values empathy and growth.

$133,000–$267,000/yr
US 12w maternity 12w paternity

  • Build, test, and deploy software in a continuous manner, contributing to technical specs and rollout plans.
  • Work with internal customers and stakeholders to ensure we’re solving the right problems.
  • Mentor and sponsor teammates to help them grow.

Pilot provides small businesses with dedicated finance experts and software to manage bookkeeping and financial management. The company has over 3,000 customers and has raised over $170 million, fostering a culture of innovation and growth.

Global Unlimited PTO

  • Own Primer's internal developer platform end to end, including CI/CD pipelines, deployment workflows, and self-service tooling.
  • Build the human-AI development loop, creating tooling and automation for coding agent workflows.
  • Treat developer productivity as a measurable system, using frameworks like DORA to identify and fix delivery bottlenecks.

Primer provides a unified infrastructure for global payments, enabling finance and payments teams to reduce complexity and capture revenue. Backed by top investors like Sofina and Accel, they operate as a remote-first, async culture with high autonomy and low bureaucracy.

Romania

  • Develop advanced bioinformatics solutions for genomic analysis and precision medicine.
  • Build, optimize, and maintain scalable pipelines for processing complex genomic data.
  • Collaborate with interdisciplinary teams in a remote environment focused on scientific excellence.

Jobgether is an AI-powered job matching platform that connects candidates with hiring companies. It uses automated processes to review applications and provide a shortlist to employers, aiming for fair and efficient recruitment.

Europe

  • Own the self-service data and storage layer for multimodal biological datasets.
  • Build platform services that enable self-serve data access and processing.
  • Engineer security into the data layer with access control and least-privilege.

Bioptimus is building the first universal AI foundation model for biology to accelerate breakthroughs in biomedicine. They are a fast-growing startup with over $75M in funding, headquartered in Paris, with a world-class team redefining AI and life sciences.

$69,675–$87,075/yr
Canada

  • Author and maintain Terraform for Snowflake resources across a multi-account, multi-region footprint.
  • Contribute to role-based access control, schema migration tooling, and CI/CD pipelines for data warehouse operations.
  • Build and operate customer-facing financial reporting APIs and PCI-scoped ETL pipelines on AWS and Snowflake.

Marqeta is a modern card issuing platform powering companies like Uber, Square, Instacart, and Klarna. They are a publicly-traded company with a focus on innovation and collaboration, offering flexible work and a range of benefits.

Global Unlimited PTO

  • Define and own the technical GTM strategy and operating model.
  • Build, hire, coach, and retain a high-performing team of TAMs and Solutions Engineers.
  • Drive product adoption and expansion through technical engagement with customers.

LocalStack is a cloud development platform that provides secure local sandboxes for developers and AI agents to simulate cloud environments. It is a growing Series A startup with globally distributed teams, valuing compassion, ownership, and innovation.

US

  • Own the end-to-end pipeline that powers pricing recommendations, from data ingestion through ML models to customer-facing outputs.
  • Rebuild data reconciliation from property management systems, tackling hard data and orchestration challenges.
  • Build observability, alerts, and infrastructure as code across Python, Terraform, and Ruby.

We're a profitable, growth-stage company building AI and data SaaS products for the PropTech space, including ApartmentIQ and MavenAI. We're a fully remote team of 100+ with a strict no a**holes policy and a high-performance culture.

$173,000–$255,000/yr
US

  • Own bank systems end-to-end, including infrastructure, data platform, and vendor integrations.
  • Leverage AI tools as a force multiplier for code, design, and operations.
  • Partner with compliance and risk to build examiner-ready systems and documentation.

Affirm is reinventing credit to make it more honest and friendly, giving consumers flexibility to buy now and pay later without hidden fees. It is a remote-first public company with a strong engineering culture and a focus on employee wellbeing.

$160,000–$175,000/yr
Global Unlimited PTO

  • Design, build, and operate secure, scalable multi-account AWS infrastructure using Terraform with reusable modules.
  • Evolve CI/CD pipelines and deployment automation for faster, safer releases.
  • Build self-service platforms that reduce developer friction and manual operational toil.

Leap transforms the home improvement industry by building technology that helps contractors work smarter and scale faster. Recognized on the Inc. 5000 list for 5+ consecutive years, we have a transparent, supportive culture with approachable leadership and a strong eNPS score.

US

  • Lead and mentor a team of Bioinformatics Scientists in the Women's Health and Organ Health research organization.
  • Own the research strategy behind new product development, from scoping through execution.
  • Drive bioinformatics analysis for assay development, including NGS data processing and multi-omic approaches.

Natera is a global leader in cell-free DNA testing, dedicated to oncology, women's health, and organ health. The team consists of highly dedicated professionals from world-class institutions who care deeply for their work.

$200,000–$235,000/yr
US 2w PTO

  • Handle infrastructure work across a growing scope — from hand-picked, low-urgency familiarization tasks toward independently managing significant components.
  • Troubleshoot and resolve infrastructure issues with autonomy, seeking guidance on necessary changes and architecture decisions.
  • Engage in infrastructure-as-code projects and play an active role in CI/CD pipeline management.

Planning Center exists to help churches build stronger, more connected communities. Since 2006, over 80,000 churches have trusted our tools, and we are an independent, profitable company with no outside investors, operating with a fully remote team.

$118,000–$151,000/yr
US 4w PTO

  • Build and improve platform services, including CI/CD pipelines and cloud infrastructure.
  • Collaborate with senior engineers to design scalable solutions and enhance developer experience.
  • Participate in incident response and retrospectives to drive continuous improvement.

Octopus Energy is a tech-powered energy company focused on renewable energy and customer experience. The company culture emphasizes ownership, collaboration, and making a tangible impact across teams.

$80,000–$120,000/yr
Global Unlimited PTO

  • Design and scale reliable AWS infrastructure across multiple accounts, ensuring security and compliance.
  • Collaborate with software engineers to advise on infrastructure best practices and optimize CI/CD pipelines.
  • Automate critical infrastructure updates and enhance observability with monitoring tools like Prometheus.

Constructor is an AI-first ecommerce search and discovery platform that helps shoppers find the right products and enables leading global e-commerce brands to drive revenue and conversion gains. They are a fully remote, diverse team offering unlimited vacation, training budgets, and the chance to work with smart colleagues.

Global

  • Design and maintain AWS infrastructure using Terraform, with a focus on scalability cost and PCI-scoped network segmentation
  • Build and evolve the observability stack and CI/CD pipelines to ensure smooth production operations and rapid deployment
  • Lead incident response define SLOs and run performance tests to optimize payment-critical services

Xplor Technologies provides vertical software, embedded payments, and AI tools for membership-based and service-based industries. With over 130,000 businesses in 72+ countries and processing $47 billion in payments annually, the company values diversity, collaboration, and a people-first culture.