Source Job

US

  • Own the application engineering strategy and execution across backend, mobile, and desktop.
  • Lead and grow a small, senior applications team, including backend, mobile, and desktop engineers.
  • Set the architectural direction for Artificial Intelligence (AI)-powered product workflows, APIs, and client integrations.

Artificial Intelligence Machine Learning Backend Engineering System Design API Integration

20 jobs similar to VP of Engineering Applications, Artificial Intelligence (AI) Required, Work From Home

Jobs ranked by similarity.

US

  • Own the application engineering strategy and execution across backend, mobile, and desktop.
  • Lead and grow a small, senior applications team.
  • Ensure production-grade reliability and integration of AI capabilities.

We help companies hire technical leads and IT professionals for jobs in San Francisco and other cities. We are a recruiting agency focused on IT staffing.

US Unlimited PTO 16w maternity 16w paternity

  • Design, build, and deploy AI-powered solutions connecting Remote’s platform to customer systems and workflows.
  • Work at the frontier of practical AI, shipping reliable, observable, and secure systems in production.
  • Own customer outcomes from discovery through production rollout with high autonomy and direct influence on product roadmap.

Remote is a global HR platform that helps businesses recruit, pay, and manage international teams compliantly. The company fosters a future-focused, async culture with team members across 6 continents and emphasizes innovation, automation, and AI.

US

  • Serve as primary technical advisor to customers, leading discovery sessions and translating business priorities into AI-enabled solutions.
  • Lead cross-functional engineering teams to design and deploy secure, scalable, and high-performing AI software systems.
  • Mentor engineers, establish engineering standards, and drive delivery of enterprise-scale AI solutions.

LTS delivers AI-powered software solutions for complex business and mission challenges. The company values innovation, growth, collaboration, and quality, and offers a culture that rewards ambition and performance.

United States

  • Lead and grow a geographically aligned engineering organization at the director level, owning regional P&L and ensuring successful delivery of client and internal initiatives.
  • Champion adoption of AI-forward tools and AI-assisted delivery, raising both velocity and expertise across the team.
  • Set the standard for AI-forward engineering practice, using tools like Claude and Cursor with sophistication, and help the team adopt AI tools effectively.

Robots & Pencils is an applied AI engineering firm building AI co-workers for enterprise operations. Founded in 2009 with delivery centers in Canada, the US, Eastern Europe, and Latin America, they are a nimble, senior-led team averaging 15+ years of experience.

Vietnam

  • Build AI-powered workflows, assistants, agents, and automation systems across customer support, CRM, and finance operations.
  • Work with product and engineering teams to turn manual processes into scalable AI-native systems using LLMs, APIs, and internal data.
  • Prototype quickly, test with users, then productionize what works, ensuring evaluation, monitoring, and reliability.

Bjak believes people deserve smarter ways to plan, save and grow their money, starting with the first mobile-first insurance platform in Southeast Asia. They have teams worldwide with over 20 nationalities working from offices and remotely, seeking talented and driven people.

$148,000–$203,500/yr
Global Unlimited PTO

  • Own the design and evolution of core capabilities for the internal AI agent platform to support high-impact business workflows.
  • Partner with cross-functional teams to translate strategic goals into scalable AI agent solutions.
  • Build and maintain shared services, deployment patterns, and observability frameworks for reliable agent deployment.

ActiveCampaign is the autonomous marketing platform that enables teams to automate campaigns with AI agents. It is a global, multicultural company with a fast-growing, collaborative culture.

United States Canada Unlimited PTO

  • Build the internal AI deployment platform, making it possible for non-engineers to safely run AI workflows at scale.
  • Ship high-leverage agentic workflows across Marketing, Sales, Support, Finance, and Operations.
  • Lead a mixed team of engineers, product managers, and business users to drive AI adoption across the company.

Wrapbook is a fintech platform that enables companies to onboard, pay, and insure their project-based workforces, focusing on the entertainment industry. With over $30M raised from investors like Andreessen Horowitz, they are at a stage of rapid growth with a culture that blends creativity and technology.

US

  • Write behavioral specs, architectural constraints, and feature requirements that agents implement against.
  • Build and maintain harness infrastructure including structural tests, linting rules, and CI gates.
  • Design validation systems where agents write the tests and you verify features work from the user's perspective.

Bolo.ai builds generative AI systems for the energy industry, making daily work faster, safer, and better for heavy industry workers. We have Fortune 500 contracts, production deployments, and growing enterprise demand, and we're scaling with a small, senior-leaning engineering team.

Global

  • Define long-term architecture for AI systems, infrastructure, and developer platform.
  • Build and scale a world-class engineering team across key talent hubs including China and US.
  • Work closely with product, research, and leadership teams to ensure technical workstreams move forward smoothly.

$140,000–$190,000/yr
US

  • Build end-to-end product features across frontend, backend, and AI integrations.
  • Design agent workflows that handle planning, tool use, failure, and recovery across multiple steps.
  • Integrate LLMs, memory, and external tools into systems that behave reliably under real-world conditions.

Gina's Tech Jobs is a recruiting agency that connects companies with tech talent. They work with a range of IT positions and focus on helping companies hire for roles like this one.

$224,000–$256,000/yr
US

  • Drive AI strategy and build multi-agent systems to re-engineer internal operations across all functions.
  • Ship production-grade AI workflows, ensuring HIPAA compliance and secure integration with core systems.
  • Coach non-technical teams and scale adoption through training and reusable frameworks.

Tebra is the only all-in-one EHR+ platform built exclusively for independent healthcare practices. With more than 42,000 private practices trusting Tebra, the company is dedicated to reducing burnout and helping clinicians rediscover their purpose.

$220,000–$245,000/yr
US Unlimited PTO 14w maternity 14w paternity

  • Lead, manage, and grow a distributed engineering team dedicated to AI platform development.
  • Own the technical strategy and roadmap for Cohere's AI platforms, applications, and agents.
  • Design data and semantic architectures to provide AI agents with accurate healthcare data.

Cohere Health's clinical intelligence platform uses agentic AI to optimize care for health plans and providers, covering over 15 million people. The company has been recognized as a top LinkedIn startup and is backed by leading investors.

$100,000–$100,000/yr
Global

  • Design and execute AI-native software development experiments to measurably improve productivity, quality, and speed.
  • Evaluate emerging AI engineering tools and institutionalize development, testing, and delivery standards.
  • Coach engineers and leaders across the organization to adopt AI-assisted workflows and drive transformation.

Sparkrock helps social benefit organizations—such as nonprofits, school boards, and government agencies—operate more effectively. They are a global, fully remote organization dedicated to mission-driven enterprise software.

LATAM

  • Build and ship AI workflow solutions including prompt architectures, automation flows, lightweight agents, and API integrations.
  • Embed in business teams across Finance, HR, Legal, Marketing Ops, and Customer Success to understand workflows and create leverage.
  • Support the AI Program Office by building demos, prototypes, and contributing to vendor evaluations.

Backblaze is the object storage leader in the open cloud movement, fueling customer success with cloud storage built purposefully. Founded in 2007, the company generates over $100 million in revenue and manages over three billion gigabytes of data for 500,000+ customers in 175+ countries.

Global

  • Lead a team of around 20 engineers across backend platform, frontend platform, DevOps, architecture, accessibility, and quality assurance.
  • Set the platform technology strategy and own its execution, from cloud infrastructure to internal developer platform to AI tooling.
  • Mentor engineers and managers, providing support for role and career development.

Frontify helps brands turn ideas into impact by transforming how teams organize digital assets, collaborate on projects, and create engaging campaigns. With headquarters in St. Gallen, Switzerland, and offices in London and New York City, we share a vibrant culture built on creativity, collaboration, inclusion, and joy.

UK

  • Partner with enterprise clients to understand challenges and design robust technical solutions, from APIs to AI workflows.
  • Own production deployments ensuring reliability, observability, and continuous improvement of delivered systems.
  • Build AI-enabled systems using LLMs and agentic workflows while collaborating across Product, Engineering, and Sales teams.

Our partner is a company focused on deploying AI and enterprise integrations at scale. They operate in a remote-first, high-trust environment with a focus on practical AI deployment.

$173,000–$233,000/yr
Canada

  • Build and ship AI agents, APIs, and applications on Affirm's internal platform, owning the full lifecycle from architecture to production.
  • Turn messy business requirements from People Operations stakeholders into production systems, integrating with tools like Workday and Notion.
  • Design reliability infrastructure for multi-model LLM services, including structured output validation and quality controls.

Affirm is reinventing credit to make it more honest and friendly, giving consumers the flexibility to buy now and pay later without any hidden fees or compounding interest. The People Tech & Analytics team builds and owns the data, AI, and technology infrastructure for Affirm's People function, running like a product engineering group embedded in HR.

US 5w PTO

  • Lead engineering execution, manage a senior team, and contribute to the codebase for Thunderbolt's AI product.
  • Partner with leadership to turn product direction and AI strategy into coordinated engineering plans with strong quality standards.
  • Build scalable operating models and practices for a production-ready open-source AI product.

MZLA Technologies Corporation, the nonprofit-owned company behind Thunderbird, builds privacy-respecting communication and productivity tools. With over 20 million users and a team of 60+ people across seven countries, they operate collaboratively and inclusively within the Mozilla family.

Global

  • Drive engineering execution and structure workstreams to ensure reliable delivery.
  • Provide technical guidance on system architecture and design decisions.
  • Build and scale a high-performing engineering team across global locations.

Next Step Systems is an IT recruiting agency specializing in placing engineering professionals. They have a dedicated team focused on connecting talent with opportunities, fostering a collaborative and supportive culture.

$160,000–$210,000/yr
US Unlimited PTO

  • Evaluate and select cutting-edge AI models to enhance product capabilities and user experience.
  • Design evaluation frameworks and configure observability for AI performance in production.
  • Collaborate with data science, CTO, and engineering teams to fine-tune and integrate AI models.

Vetcove modernizes veterinary software and pet healthcare with a procurement marketplace, home delivery ecommerce, and practice management system. Over 25,000 hospitals across all 50 states use the platform daily, and the company is backed by Y Combinator and top venture investors.