Source Job

$290,000–$380,000/yr
United States

  • Lead the clinical development strategy for AL137, owning the medical strategy for Phase 1 and shaping the path toward later-stage development.
  • Provide medical leadership for protocol design, safety considerations, dose escalation, and data interpretation in early clinical trials.
  • Serve as the internal physician expert, integrating AI technologies to accelerate analysis and improve decision-making.

Clinical Development Neuroscience Drug Development Clinical Trial Design AI/LLMs

20 jobs similar to Senior Director, Clinical Development

Jobs ranked by similarity.

US

  • Leads the delivery of high-priority AI and operational transformation initiatives, partnering with IT and Development teams.
  • Owns end-to-end delivery accountability, managing scope, timeline, budget, and risk.
  • Establishes program governance, reporting, and value realization metrics to drive business outcomes.

Ultragenyx is a biopharmaceutical company committed to developing life-changing treatments for rare diseases. They foster a supportive and inclusive culture focused on continuous learning and growth.

US

  • Drive lifecycle strategy to expand the impact of late-stage and marketed assets across new indications and formulations.
  • Lead early clinical development including first-in-human studies and data-driven dose selection.
  • Provide pipeline-wide clinical leadership and represent Praxis with health authorities and partners.

Praxis Precision Medicines is a clinical-stage biopharmaceutical company translating genetic insights into therapies for central nervous system disorders. The company fosters a culture of trust, ownership, curiosity, and results, with a collaborative team focused on high-impact medicines.

$268,000–$302,000/yr
US

  • Provide strategic scientific leadership for clinical pharmacology across all development phases from Phase 1 through Phase 3.
  • Design and oversee clinical pharmacology studies, including PK/PD, exposure-response, and modeling and simulation activities.
  • Collaborate with cross-functional teams and support regulatory submissions to global health authorities.

Amylyx is a clinical-stage biotechnology company focused on developing therapies for diseases with high unmet needs, including ALS, Wolfram syndrome, and post-bariatric hypoglycemia. The company fosters a culture of caring with core values of audacity, curiosity, authenticity, engagement, and accountability, and has assembled an experienced team ready to tackle tough medical problems.

$204,000–$240,000/yr
US Unlimited PTO

  • Step into critical ownership gaps and build the operating model for major initiatives.
  • Drive business outcomes by harnessing AI and emerging technology to solve healthcare problems.
  • Lead through ambiguity, stabilize underbuilt areas, and prepare for long-term handoff.

Clover is reinventing health insurance by combining data with human empathy to keep members healthier. They are a mission-driven team with diverse expertise, working to solve the most complicated problem in healthcare.

$291,250–$338,750/yr
US Unlimited PTO

  • Lead and evolve a bold, user-centered vision for design and UX across the product portfolio, driving AI-forward strategy.
  • Build, mentor, and grow a team of senior design leaders, and scale the organization in alignment with company growth.
  • Own key metrics tying design and AI initiatives to user satisfaction, adoption, and revenue outcomes.

Smartsheet empowers teams to manage work seamlessly and scale solutions, now uniting human teams with AI agents. They have been in business for over 20 years and foster a culture of innovation, collaboration, and impact.

$220,000–$275,000/yr
US Canada

  • Lead design across Later's product portfolio, setting design standards, patterns, and processes for cohesive, scalable experiences.
  • Drive AI-native UX workflows and rapid prototyping, using generative AI to accelerate from idea to validated experience.
  • Mentor and elevate a team of UX designers, shifting culture from traditional screen-design to an AI-native, builder-first mindset.

Later is an AI-powered influencer marketing platform trusted by major brands like Nike, Wayfair, Unilever, and Southwest Airlines. With a team of over 100 developers, they foster a culture of rigor, accountability, and collaboration without ego.

North America

  • Serve as the strategic operating leader for ServiceNow's Enterprise AI organization, driving operating cadence and governance.
  • Build executive-ready mechanisms for prioritization, decision making, and cross-functional accountability.
  • Develop portfolio-level visibility and measure ROI for AI initiatives in partnership with finance and AI Champions.

ServiceNow is the AI control tower for business reinvention, offering a platform that integrates AI, data, and workflows to help 85% of the Fortune 500 work smarter. The company fosters an AI-native culture where technology and talent are unstoppable together, aiming to free people from busywork.

$228,700–$285,900/yr
US Canada

  • Define and evolve Mercury's interaction philosophy, focusing on AI-native, conversational, and adaptive experiences.
  • Lead, coach, and develop a team of product designers to produce exceptional work and take creative risks.
  • Shape product strategy alongside Product and Engineering, bringing design into ambiguous problems early.

Mercury is a fintech company that provides banking services through partnerships with FDIC-insured banks. The design organization consists of 40+ people who love solving complex problems and are passionate about cultivating and inspiring one another.

US

  • Drive product vision and strategy for AI and Lab Products at Absci.
  • Lead interdisciplinary teams of AI/ML researchers, engineers, and scientists to build delivery platforms.
  • Serve as bridge between AI Research and Biologics Discovery Technology teams for drug design and target identification.

Absci is a clinical-stage biotechnology company using generative AI to design novel therapeutics. It is a global company headquartered in Vancouver, WA, with offices in New York City, Switzerland, and Serbia.

US Unlimited PTO

  • Define the next generation of Komodo's AI product suite by building and shipping working software.
  • Own the thesis for what customers touch, study how they work, and revise as models improve.
  • Build first versions with AI tools, deploy forward inside customer environments, and set the pattern for future surfaces.

Komodo Health reduces the global burden of disease by building the Healthcare Map, the industry's largest view of the U.S. healthcare system. They value being awesome, seeking growth, delivering 'wow,' and enjoying the ride, with a team of ambitious, supportive Dragons.

$199,000–$267,950/yr
US 4w PTO

  • Own end-to-end development of core AI capabilities, from research to production.
  • Define and drive personalization tech strategy, influencing roadmap across teams.
  • Mentor and raise the bar for the team through technical mentorship and evaluation practices.

Oura designs and sells smart rings that track health metrics to help users improve their well-being. They are a rapidly growing company with a global community of millions of users and a supportive, employee-focused culture.

US

  • Own strategic AI build partnerships end to end, from pre-sales discovery to delivery and handoff.
  • Lead executive workshops to identify high-value workflows and translate them into scoped AI solutions.
  • Validate solutions achieve measurable outcomes and mentor early-career architects.

AcuityMD is a software and data platform that helps MedTech companies accelerate access to medical technologies through data and AI. It is a high-growth startup backed by leading investors, with a remote-first culture and a focus on mentorship and inclusion.

US Unlimited PTO

  • Lead the development of the AI-powered product suite for clinicians and patient/provider growth.
  • Own the AI codebase as the most senior engineer, building alongside offshore engineers and growing the team.
  • Work across product, engineering, and clinical teams to deliver personalized care.

Allswell is building the leading mental health company for the LGBTQ+ community, providing affirming, high-quality care. Backed by leading healthcare and impact investors, the company has served hundreds of clients and reports strong clinical outcomes.

US

  • Serve as the Development authority on end-to-end Development lifecycle workflows, identifying opportunities for AI and automation.
  • Re-engineer and redesign workflows to embed AI effectively, optimizing processes for efficiency and quality.
  • Partner with IT to translate business needs into requirements and ensure solutions are scalable and compliant.

Ultragenyx is a biopharmaceutical company dedicated to developing innovative treatments for rare diseases. They foster a supportive and inclusive culture focused on profound learning and growth.

US Unlimited PTO

  • Partner with the CCO to drive strategic initiatives across Customer Success, Operations, and Programming.
  • Lead the PMO by prioritizing, delegating, tracking, and driving initiatives to measurable outcomes.
  • Own community management and growth, building a playbook to drive engagement and scaling the active community 3-5x.

NewtonX is a B2B insights company that combines a verified network of business professionals with AI-powered research tools to deliver research intelligence. The company has raised $47M from investors and serves clients like Google, Microsoft, and Stripe, fostering a diverse and collaborative culture.

US

  • Ensure clinical safety and operational efficiency of AI agent deployments.
  • Drive clinician adoption and confidence in AI tools through training and support.
  • Identify new use cases and workflows where AI can transform care delivery.

Hippocratic AI is building safety-first generative intelligence for healthcare. The company emphasizes clinical safety, patient advocacy, and cross-functional collaboration in a remote-first environment.

$250,000–$260,000/yr
US Unlimited PTO 12w maternity 12w paternity

  • Partner with Product and Engineering leadership on clinical decisions for Trust & Safety and error detection.
  • Monitor and analyze AI-generated clinical errors, quantify trends, and conduct root cause analysis.
  • Provide clinical leadership for SafeRead human-in-the-loop review and supervise clinical specialists.

SmarterDx is a clinical AI company helping health systems capture the full value of patient care through clinically-sound recommendations for revenue cycle teams. They are a remote-first team of mission-driven colleagues building technology to make healthcare more accurate and sustainable.

$130,000–$150,000/yr
US

  • Build agentic AI systems for rare disease research, including conversation logic and validation steps.
  • Model outputs in Pydantic with structured output and tool calling to ensure typed and traceable fields.
  • Write and test prompts for clinical and scientific reasoning tasks, treating prompts as code.

Axle is a bioscience and IT company advancing translational research and data science for healthcare organizations. They collaborate with top research facilities including NIH and emphasize diversity and innovation.

$210,000–$255,000/yr
United States

  • Lead strategic development and continuous evolution of the Medical Information function to support COMP360 and pipeline assets.
  • Oversee development of compliant medical information response documents and collaborate cross-functionally to ensure alignment.
  • Establish scalable capabilities, metrics, and innovation in technology and service delivery to enhance operational excellence.

Compass Pathways plc is a biotechnology company dedicated to developing new treatment options in mental health care, with a focus on COMP360 psilocybin for treatment-resistant depression and PTSD. The company is headquartered in London, UK, with a US office in New Jersey, and leads one of the largest clinical programs in psychedelic treatments.

US

  • Own and solve ambiguous, high-stakes problems across strategy, operations, client delivery, and organizational priorities.
  • Partner with senior leadership on strategic initiatives, fundraising, business development, and AI transformation projects.
  • Drive hands-on execution, including data initiatives, client projects, and AI-powered productivity enhancements, with significant autonomy.

The company is a high-growth organization focused on AI transformation, entrepreneurship, and investment, operating within a venture studio environment. It values autonomy, ownership, and a low-ego, high-accountability culture, offering direct exposure to senior leadership and strategic decision-making.