Source Job

$175,000–$200,000/yr
US

  • Lead technical execution of complex AI initiatives, designing and delivering ML and LLM systems for patient and provider-facing products.
  • Own problems end-to-end: scope with clinicians, build datasets, iterate on modeling, and ship to production with monitoring and guardrails.
  • Develop robust evaluation frameworks including offline benchmarks, human-in-the-loop review, and online experiments to ensure model safety and accuracy.

Python Machine Learning Large Language Models Generative AI Software Engineering

20 jobs similar to Senior Applied AI Engineer

Jobs ranked by similarity.

US 24w maternity 24w paternity

  • Build the AI Platform Foundation by leading design and ownership of core infrastructure.
  • Standardize the AI Developer Path by architecting high-level abstractions and APIs.
  • Engineer AI Trust & Safety Systems through monitoring and quality assurance layers.

Smartsheet provides a collaborative work management platform. As a publicly traded company with thousands of employees, it fosters a culture of innovation and inclusion.

$250,000–$265,000/yr
US Unlimited PTO 16w maternity 8w paternity

  • Design and build core architecture for AI systems spanning multiple product areas, ensuring coherence and reuse.
  • Set the technical bar for the org in evaluation frameworks, testing philosophy, CI/CD for model behavior, and shared infrastructure.
  • Take direct ownership of the hardest, most ambiguous technical problems and build solutions end-to-end.

Twin Health empowers people to prevent and reverse chronic metabolic diseases using AI Digital Twin technology. The company is rapidly scaling across the U.S. and globally with over $100 million raised, and has been recognized as an innovator and top workplace.

Global

  • Lead the development of our patient-facing conversational agent
  • Implement scalable, low-latency systems for voice and multimodal conversations
  • Work with clinical experts to validate performance and medical accuracy

UpDoc is building the first clinically validated, physician-supervised AI agent that manages chronic diseases. It is an early-stage startup founded by Stanford physicians.

US

  • Lead applied AI investments, owning technical direction for high-impact AI products and shipping systems across teams.
  • Collaborate cross-functionally to define and execute AI product innovation and engineering execution.
  • Help raise the bar for how we build, evaluate, and operate AI in production at scale.

Rula is a mental health company dedicated to treating the whole person with evidence-based and compassionate care. As a remote-first company, we hire in most U.S. states and focus on creating a culture of inclusion and well-being for our employees.

$150,000–$175,000/yr
US

  • Design and deploy AI/ML and Generative AI models to drive operational efficiencies across VBC and RCM datasets.
  • Implement advanced architectures including LLMs, RAG, and agentic frameworks, and build end-to-end pipelines using Python, PySpark, or T-SQL.
  • Apply MLOps best practices and work with cloud platforms like GCP to ensure scalable and responsible AI deployments.

Privia Health is a technology-driven national physician enablement company that collaborates with medical groups, health plans, and health systems to optimize physician practices and improve patient experiences. The company is led by top industry talent and focuses on reducing healthcare costs through cloud-based technology and scalable operations.

US

  • Develop and operate production-ready AI and machine learning systems for enterprise-scale products.
  • Build and optimize LLM-powered applications, RAG pipelines, and intelligent agents.
  • Implement software engineering best practices for AI development including CI/CD and testing.

Our partner is building enterprise-grade AI solutions that deliver measurable business impact. They offer a remote-friendly work environment with a collaborative engineering culture focused on innovation, quality, and continuous learning.

$219,245–$290,000/yr
US

  • Set technical direction for complex GenAI and agentic systems, building them hands-on and raising the bar for production-ready AI.
  • Own the hardest problems in AI portfolio, from agentic platforms at scale to AI in regulated, high-stakes environments.
  • Partner directly with client leadership to translate business strategy into AI architecture and shape solutions in pre-sales.

Egen is a fast-growing and entrepreneurial company with a data-first mindset, helping clients drive action and impact through data and insights using advanced technology platforms like Google Cloud and Salesforce. We are committed to being a place where the best people choose to work, dedicated to learning, thriving on solving tough problems, and continually innovating to achieve fast, effective results.

$90,000–$150,000/yr
United States

  • Design and deliver production AI and agentic systems across document intelligence, workflow automation, and copilots.
  • Own architecture decisions for LLM-based systems, including retrieval, tool use, orchestration, memory, and evaluation.
  • Manage evals and observability for production AI, ensuring system accuracy and detecting regressions.

Maxwell is a mortgage technology and fulfillment company on a mission to make lending simpler, faster, and more accessible. It is a remote-first team that takes craft seriously and moves with intention, building a cutting-edge AI company in mortgage technology.

Brazil

  • Provide technical leadership and mentorship to junior engineers on the Applied AI team.
  • Design and implement scalable architectures for LLM-based applications, including agents and vector databases.
  • Develop evaluation pipelines and prototype components to validate AI product concepts.

Jobgether is an AI-powered job matching platform that connects candidates with hiring companies. They prioritize fair and efficient recruitment, fostering an inclusive and diversity-driven workplace culture.

$160,000–$180,000/yr
US

  • Build production-grade AI systems that enhance organizational intelligence and operational efficiency.
  • Collaborate with cross-functional teams to turn ambiguous AI opportunities into safe, measurable product capabilities.
  • Design and maintain scalable backend services, data pipelines, and human-in-the-loop workflows.

Honor Technology changes how society cares for older adults by providing technology, tools, and services for in-home care. With a global franchise network and over 100,000 Care Pros, Honor delivers 50 million hours of personalized care annually, fostering a culture of compassion and innovation.

$180,000–$180,000/yr
US

  • Own the technical vision and implementation of AI capabilities for MRO's healthcare products, including RAG pipelines and LLM integrations.
  • Architect and evolve production AI systems with human-in-the-loop feedback and model quality frameworks.
  • Collaborate with product, data engineering, and engineering teams to translate complex healthcare workflows into scalable, accurate, and compliant AI solutions.

MRO is a healthcare software company that builds AI-powered solutions for healthcare registry management. They are a full-time, remote-first organization with a focus on compliance and quality.

EU

  • Design, build and evolve scalable ML and generative AI systems delivering measurable value in customer-facing and operational use cases.
  • Develop robust end-to-end pipelines for training, evaluation, deployment, monitoring, and continuous improvement of AI solutions in production.
  • Collaborate closely with product, engineering, data, and business stakeholders to bring AI capabilities into core digital healthcare systems and operations.

Redcare Pharmacy is Europe's No.1 e-pharmacy, powered by passionate teams and cutting-edge innovation. We strive to create a healthy collaborative work environment where every employee feels valued and inspired to contribute to our vision.

US 24w maternity 24w paternity

  • Design and build production-grade LLM-powered agents and workflows for enterprise-scale AI solutions.
  • Develop and optimize RAG pipelines, agent reasoning patterns, and evaluation frameworks to measure model quality.
  • Collaborate with Engineering, Product, and cross-functional teams to translate business requirements into impactful AI systems.

Smartsheet builds AI-powered strategic planning and work execution agents through SmartAssist, an intelligent agent platform. The company is a publicly traded, large enterprise with a collaborative, inclusive culture that values diverse perspectives and engineering rigor.

Brazil

  • Lead the design and delivery of scalable Generative AI solutions, acting as a technical reference and defining architecture standards.
  • Build AI agents, multi-agent workflows, and integrate LLMs with APIs, ensuring security and compliance with regulations like HIPAA.
  • Drive POC lifecycle management, quality testing for non-deterministic flows, and mentor mid-level and junior engineers.

CI&T helps large enterprises transform AI potential into real business impact with AI deployment and tech-integrated solutions. With 30 years of experience and 8,000 employees across 25 countries, they foster a culture of collaboration and innovation.

Europe

  • Design, build, and operate AI systems that solve real business problems across Finom, from prototype to production.
  • Own AI systems end-to-end including problem framing, architecture, implementation, evaluation, deployment, monitoring, and iteration.
  • Partner with solution managers, domain teams, and engineers to integrate AI into real workflows and deliver production-grade AI capabilities.

Finom is a European tech startup developing an all-in-one financial B2B solution integrating banking, accounting, and invoicing. With over $346 million in total funding, they are expanding across key EU markets and maintain a start-up culture focused on innovation and employee empowerment.

Global

  • Develop and integrate ML, NLP, and Generative AI models to create smart collaborative solutions.
  • Build and optimize agentic workflows using LangChain, LangGraph, and similar frameworks.
  • Collaborate with engineering and product teams to deliver AI-driven features and prototype tools.

We are a technology company building next-generation AI-powered workplace assistants. Our team values innovation, engineering excellence, and continuous learning in an open and supportive environment.

India

  • Architect and ship production-grade agentic AI applications including multi-agent orchestration, retrieval systems, and evaluation pipelines.
  • Design and build learner-facing AI experiences and operator tools end-to-end using React and TypeScript.
  • Own production reliability for AI systems including model failover, rate limiting, cost monitoring, and incident response.

Chegg Skills builds applications that help motivated career switchers transition into high-growth roles. The company serves thousands of learners and educators each year through a high-ownership engineering team rethinking modern education.

$185,000–$200,000/yr
United States

  • Design and deliver advanced AI solutions for legal and compliance operations at enterprise scale.
  • Build end-to-end AI applications using LLMs, RAG, and agentic frameworks with Python and modern orchestration tools.
  • Partner with legal stakeholders to identify automation opportunities and develop secure, scalable production systems.

Jobgether uses AI-powered matching to connect candidates with hiring companies, streamlining the application process. They operate remotely and focus on efficient, technology-driven recruitment.

Germany

  • Design, build, and operate multi-agent workflows and tool-enabled agents for resilient production pipelines.
  • Architect and maintain end-to-end RAG systems covering document ingestion, chunking, embedding, retrieval, and answer synthesis.
  • Define and own evaluation frameworks for generative outputs, including automated metrics, LLM-as-judge, and hallucination detection.

Mitratech builds world-class products that simplify operations in Legal, Risk, Compliance, and HR functions. With over 35 years of experience, we serve 20,000 client companies globally, including 30% of the Fortune 500, and foster a diverse, inclusive culture centered on individual excellence and learning.

US 6w PTO

  • Build multi-agent AI systems and automation platforms for Marketing Operations at scale.
  • Design and implement LLM integrations, backend services, and agentic workflows.
  • Partner with cross-functional teams to identify high-impact automation problems and ship measurable solutions.

Grafana Labs is the company behind the open observability cloud, offering a fully managed platform with AI capabilities to help organizations monitor and optimize their systems. With over 1,600 team members across 40+ countries and backed by top investors, we maintain a 100% remote, collaborative culture rooted in open source and innovation.